ArticleSensors (Basel, Switzerland)2025
A ZIF-8-Based High-Performance Glucose Electrochemical Detection Platform Constructed Using a Multi-Layer Interface Optimization Strategy.
Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
To meet the demand for rapid and accurate glucose determination in clinical diagnostics, food testing, and related fields, this study developed a high-performance electrochemical glucose biosensor based on multi-walled carbon nanotubes/Prussian blue/zeolitic imidazolate framework-8@glucose oxidase/chitosan (MWCNTs/PB/ZIF-8@GOx/CS). The MWCNTs/PB conductive network significantly accelerated electron transfer and catalytic activity, while the ZIF-8, with its regular pore structure and high specific surface area, provides an efficient microenvironment for the immobilization and conformational stabilization of glucose oxidase (GOx), thereby improving substrate diffusion and maintaining enzyme activity. The MWCNTs/PB/ZIF-8@GOx/CS sensor demonstrates excellent sensing performance, featuring a wide linear response to glucose concentrations ranging from 4.8 μM to 2.24 mM, a high sensitivity of 579.57 μA/mM/cm
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