Evidence map›Paper›PMID 41305563›Full record

ArticleNutrients2025

Association Between Mini Nutritional Assessment and Health Related Quality of Life in Chinese Older Adults: A Large Cross-Sectional Study Stratified by Chronic Disease Status.

Gonghang Qiu, Zishuo Huang, Xuelan Zhao, Jiaoqi Ren, Borui Yang, Ziyi Wang, Hongfei Zhu, Shuna Lin, Liang Sun, Ying Wang and 1 more

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Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Gonghang QiuSchool of Public Health, Fudan University, Shanghai 200032, China.ORCID 0009-0009-5689-3112
Zishuo HuangSchool of Public Health, Fudan University, Shanghai 200032, China.
Xuelan ZhaoDepartment of Geriatrics, Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai 200040, China.
Jiaoqi RenDepartment of Geriatrics, Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai 200040, China.
Borui YangSchool of Public Health, Fudan University, Shanghai 200032, China.
Ziyi WangSchool of Public Health, Fudan University, Shanghai 200032, China.
Hongfei ZhuSchool of Public Health, Fudan University, Shanghai 200032, China.
Shuna LinSchool of Public Health, Fudan University, Shanghai 200032, China.
Liang SunThe NHC Key Laboratory of Geriatrics, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology of National Health Commission, Beijing 100730, China.ORCID 0000-0003-1634-4716
Ying WangSchool of Public Health, Fudan University, Shanghai 200032, China.ORCID 0000-0003-4757-1364
Houguang ZhouDepartment of Geriatrics, Huashan Hospital, National Clinical Research Center for Aging and Medicine, Fudan University, Shanghai 200040, China.

Funding

National High Level Hospital Clinical Research Funding BJ2023-314/168/075, BJ2025-126Noncommunicable Chronic Diseases-National Science and Technology Major Project 2024ZD0524200,2024ZD0524203The National Key R&D Plan "Intergovernmental International Science and Technology Key Special Project 2021YFE0111800the National Science and Technology Major Project 2023ZD0509800the National Scientific Foundation of China U23A20470
6 · The paper itself

Abstract

backgroundMalnutrition among older adults in China demands greater attention due to its significant implications for both health and functional ability. However, the relationship between nutritional status and health-related quality of life (HRQoL), especially in the context of chronic diseases, remains underexplored in the Chinese elderly population.

methodsThis large-scale cross-sectional study aimed to evaluate the association between nutritional status and HRQoL, stratified by chronic disease status, among 41,859 community-dwelling adults aged ≥ 65 years from 31 provinces in mainland China. Nutritional status was assessed using the Mini Nutritional Assessment (MNA), while HRQoL was measured using the SF-36 questionnaire; chronic disease status was based on physician diagnosis. Multiple linear regression was employed to examine the association between MNA and HRQoL, with subgroups defined by Latent Class Analysis (LCA) based on comorbidity patterns.

resultsResults revealed significant positive associations between MNA scores and SF-36 total and domain scores among participants with chronic diseases (e.g., Total: β = 0.32, 95% CI: 0.04-0.60), but not among those without chronic diseases. LCA identified four comorbidity patterns: cardiovascular-rich, metabolic-rich, musculoskeletal-rich, and relatively healthy. Significant MNA-HRQoL associations were found in the cardiovascular (β = 0.58,

conclusionsThese findings underscore the critical role of nutritional status in HRQoL among Chinese older adults with chronic diseases and highlight the need for tailored nutritional interventions in geriatric chronic disease management.

Indexed as

Geriatric AssessmentNutritional StatusNutrition AssessmentQuality of LifeAgedAged, 80 and overChinaChronic DiseaseComorbidityCross-Sectional StudiesEast Asian PeopleFemaleHumansIndependent LivingMaleMalnutritionchronic diseasescomorbidity patternsHealth-Related Quality of Life (HRQoL)latent class analysis (LCA)Mini Nutritional Assessment (MNA)older adults

Identifiers

PMID41305563
PMCPMC12655801

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.