Evidence map›Paper›PMID 41305749›Full record

Observational studyMedicine2025

Association between uric acid to albumin ratio and all-cause mortality among United States adults: An observational study.

Suling Ye, Jie Li, Liang Chen, Mengmeng Shan, Jinzhou Zhu, Lili Wang

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Diagnostic Performance of the Uric Acid-To-Albumin Ratio in Predicting Severity of Acute Pancreatitis.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suling YeDepartment of Cardiology, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, China.
Jie LiDepartment of Cardiology, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, China.
Liang ChenDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
Mengmeng ShanDepartment of Cardiology, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, China.
Jinzhou ZhuDepartment of Cardiology, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qionghai, China.
Lili WangDepartment of Cardiology, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.ORCID 0009-0006-0705-1507

Funding

Cultivation Fund of Ruijin-Hainan Hospital RJHN2024YP003
6 · The paper itself

Abstract

This study aimed to investigate if the ratio of uric acid to albumin (UAR) correlates with all-cause mortality. Smooth curve fitting was employed to analyze the association between UAR and all-cause mortality; a threshold saturation effect model was utilized to identify the inflection point of UAR's impact on all-cause mortality. Furthermore, the association between UAR and all-cause mortality from heart disease was assessed using a competing risks model. This study included 25,437 male participants and 27,090 female participants. Smooth curves fitting revealed a U-shaped relationship, demonstrating a distinct inflection point for UAR and all-cause mortality, with the inflection point for females appearing earlier than for males. Kaplan-Meier curves indicated a significantly elevated risk of death in the high UAR group (1.49 < UAR < 4.65) compared to the low UAR group (0 < UAR < 1.03). UAR emerges as a robust independent prognostic indicator for all-cause mortality and could serve as a readily accessible and valuable novel inflammatory marker for identifying high-risk patients.

Indexed as

MortalitySerum AlbuminUric AcidAdultAgedBiomarkersCause of DeathFemaleHumansKaplan-Meier EstimateMaleMiddle AgedRisk FactorsSex FactorsUnited StatesBiomarkersSerum AlbuminUric Acidall-cause mortalitycross-sectional studyNHANESUnited States adultsuric acid to albumin ratio

Identifiers

PMID41305749
PMCPMC12643609

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.