Evidence map›Paper›PMID 41305992›Full record

ArticleAnnals of laboratory medicine2026

Comparison of Plasma N-Terminal Pro-B-Type Natriuretic Peptide Levels Between European and Japanese Patients with Acute Heart Failure: An International Study.

Jolie Bruno, Aziz Daghmouri, Ayu Asakage, Camille Gobeaux, Kamilė Čerlinskaitė-Bajorė, Jelena Čelutkienė, Naoki Sato, Koji Takagi, Alexandre Mebazaa, Benjamin Deniau and 1 more

Abstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jolie BrunoINSERM UMR-S 942, Cardiovascular Markers in Stress Condition (MASCOT), Paris, France.ORCID https://orcid.org/0000-0002-6356-2284
Aziz DaghmouriDepartment of Anesthesiology and Critical Care, Groupment Hospitalier de Territoire Grand Paris Nord-Est, H?pital Andr? Gr?goire, Montreil, France.ORCID https://orcid.org/0000-0001-5648-5834
Ayu AsakageDepartment of Emergency Medicine and Critical Care, National Center for Global Health and Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4654-4065
Camille GobeauxBiochemistry Laboratory, Assistance Publique-H?pitaux de Paris, Centre-Universit? de Paris Cit?, Cochin Hospital, Paris, France.ORCID https://orcid.org/0000-0002-5237-8182
Kamilė Čerlinskaitė-BajorėINSERM UMR-S 942, Cardiovascular Markers in Stress Condition (MASCOT), Paris, France.ORCID https://orcid.org/0000-0002-6753-9356
Jelena ČelutkienėClinic of Cardiac and Vascular Diseases, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.ORCID https://orcid.org/0000-0003-3562-9274
Naoki SatoDepartment of Cardiovascular medicine, Kawaguchi Cardiovascular and Respiratory Hospital, Kawaguchi, Japan.ORCID https://orcid.org/0000-0002-5550-0083
Koji TakagiMomentum Research, Inc., Durham, North Carolina, USA.ORCID https://orcid.org/0000-0003-0213-1509
Alexandre MebazaaINSERM UMR-S 942, Cardiovascular Markers in Stress Condition (MASCOT), Paris, France.ORCID https://orcid.org/0000-0001-8715-7753
Benjamin DeniauUniversit? de Paris Cit?, Paris, France.ORCID https://orcid.org/0000-0002-5879-6369
Shiro IshiharaDepartment of Cardiovascular Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.ORCID https://orcid.org/0000-0001-9377-4301

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma biomarkers levels, essential for diagnosing cardiovascular diseases, may vary by ethnicity. In this international prospective study, we compared plasma biomarker levels between European and Asian patients with clinically similar acute heart failure (AHF). Data were collected on emergency admission for acute dyspnea. Blood samples were obtained within 4 hrs of presentation and analyzed for N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity troponin-T, growth differentiation factor 15, interleukin-6, and C-reactive protein levels. Overall, 907 AHF patients were enrolled; of which, 135 (15%) were Japanese, and 772 (85%) were European. NT-proBNP levels were significantly higher in Japanese than in Europeans [4,060 ng/L (interquartile range (IQR) 2,081-12,218) vs. 3,390 ng/L (IQR 1,410-7,682),

Indexed as

Heart FailureNatriuretic Peptide, BrainPeptide FragmentsAcute DiseaseAgedAged, 80 and overAsian PeopleBiomarkersC-Reactive ProteinEast Asian PeopleEuropeFemaleGrowth Differentiation Factor 15HumansInterleukin-6JapanBiomarkersC-Reactive ProteinGrowth Differentiation Factor 15Interleukin-6Natriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Troponin TBiomarkersEthnicityEuropeJapanNT-proBNP

Identifiers

PMID41305992
PMCPMC13071277

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.