Evidence map›Paper›PMID 41306774›Full record

ArticleResearch (Washington, D.C.)2025

EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation.

Di Yang, Lianhui Li, Kailai Zang, Wanyong Ma, Yuling Yang, Yani Sun, Bingqiang Zhang, Zunshuang Gong, Mingkang Yu, Qiyuan Du and 4 more

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Di YangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Lianhui LiDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Kailai ZangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Wanyong MaEmergency Department, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, China.
Yuling YangDepartment of Infectious Diseases, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Yani SunDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Bingqiang ZhangQingdao Restore Biotechnology Co., Ltd., Qingdao, China.
Zunshuang GongDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Mingkang YuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Qiyuan DuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Xiaokun LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Zhe WangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.
Qiyue XuDepartment of Business, Qingdao University of Technology, Qingdao, China.
Ning LiDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Qingdao Medical College, Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0002-1895-4983

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic lipid dysregulation drives metabolic dysfunction-associated steatotic liver disease (MASLD); nonetheless, the precise regulatory mechanisms remain incompletely elucidated. In this study, we examine the function of EVA1A, a known hepatocellular carcinoma tumor suppressor, in hepatic lipid metabolism. Hepatic EVA1A was markedly down-regulated in individuals diagnosed with MASLD, as well as in mice subjected to a high-fat diet. Hepatocyte-specific knockout of

Identifiers

PMID41306774
PMCPMC12645495

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.