Evidence map›Paper›PMID 41306986›Full record

ArticleNPJ cardiovascular health2025

Feature extraction tool using temporal landmarks in arterial blood pressure and photoplethysmography waveforms.

Ravi Pal, Akos Rudas, Tiffany Williams, Jeffrey N Chiang, Anna Barney, Maxime Cannesson

Abstract read
In one paragraph

Article in NPJ cardiovascular health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Wearable Flexible Sensors for Cardiovascular Disease Monitoring.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  2. Article
  3. Article
  4. Vascular waveform analysis using Bayesian pulse deconvolution.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ravi PalDepartment of Anesthesiology & Perioperative Medicine, University of California, Los Angeles, CA USA.
Akos RudasDepartment of Computational Medicine, University of California, Los Angeles, CA USA.
Tiffany WilliamsDepartment of Anesthesiology & Perioperative Medicine, University of California, Los Angeles, CA USA.
Jeffrey N ChiangDepartment of Computational Medicine, University of California, Los Angeles, CA USA.
Anna BarneyInstitute of Sound and Vibration Research (ISVR), University of Southampton, Southampton, UK.
Maxime CannessonDepartment of Anesthesiology & Perioperative Medicine, University of California, Los Angeles, CA USA.

Funding

Machine Learning of Physiological Waveforms and Electronic Health Record Data to Predict, Diagnose, and Treat Hemodynamic Instability in Surgical PatientsR01HL144692 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CANNESSON, MAXIME · 2019 to 2023
$3.5M
Biomedical Informatics Tools for Applied Perioperative PhysiologyR01EB029751 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CANNESSON, MAXIME · 2020 to 2023
$2.5M
Personalized Risk Prediction for Prevention and Early Detection of Postoperative Failure to RescueR01EB035028 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Maxime Cannesson · 2023 to 2026
$2.3M
NHLBI NIH HHS R01 HL144692NIBIB NIH HHS R01 EB029751NIBIB NIH HHS R01 EB035028
6 · The paper itself

Abstract

This study presents an automatic feature extraction tool that first detects temporal location of landmarks within each cardiac cycle of ABP and PPG waveforms, including the systolic phase onset, systolic phase peak, dicrotic notch, and diastolic phase peak. Then, based on these landmarks, extracts 852 features per cardiac cycle, encompassing time-, statistical-, and frequency-domains. The tool's ability to detect landmarks was evaluated on the perioperative MLORD dataset comprising 17,327 patients and on real-time data collected from a patient monitor (retrospective analysis). When compared with markings by an experienced researcher, the tool demonstrated robust performance across both datasets, waveform types, and all four landmarks, achieving average F1-scores above 97% and error rates below 4%. This tool has significant potential for supporting clinical utilization of ABP and PPG waveform features and for facilitating feature-based machine learning models for various clinical applications where features derived from these waveforms play a critical role.

Indexed as

CardiologyDiseasesHealth careMedical research

Identifiers

PMID41306986
PMCPMC12643918

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.