Evidence map›Paper›PMID 41307635›Full record

ArticleThe ultrasound journal2025

Lung ultrasound for etiological diagnosis of pneumonia in the emergency department: correlation with bronchoalveolar lavage results.

Lorenzo Pelagatti, Iacopo Vannini, Francesca Mangani, Gian Maria Rossolini, Giovanni Volpicelli, Simone Vanni, Peiman Nazerian

Abstract read
In one paragraph

Article in The ultrasound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenzo PelagattiEmergency Department, Careggi University Hospital, Largo Brambilla 1, Florence, 50134, Italy. pelagattil@aou-careggi.toscana.it.ORCID http://orcid.org/0000-0003-1849-8372
Iacopo VanniniEmergency Department, Careggi University Hospital, Largo Brambilla 1, Florence, 50134, Italy.
Francesca ManganiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Gian Maria RossoliniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0002-9386-0434
Giovanni VolpicelliDepartment of Medical and Surgery Science, Magna Graecia University, Catanzaro, Italy.
Simone VanniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0002-1201-5715
Peiman NazerianEmergency Department, Careggi University Hospital, Largo Brambilla 1, Florence, 50134, Italy.ORCID http://orcid.org/0000-0003-1072-9148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumonia is the leading cause of death from infectious diseases worldwide. Lung ultrasound (LUS) is highly accurate for chest infections diagnosis, yet its correlation with causative pathogens remains unclear. Respiratory cultures, combined with molecular techniques represent the gold standard, achieving etiological diagnosis in 90-95% of cases. We compared LUS findings with bronchoalveolar lavage (BAL) sample analyses; to our knowledge, no prior studies have investigated this in the emergency department (ED). MATERIALS AND

methodsBronchoalveolar lavage (BAL)-LUS is a prospective observational non-profit study conducted in the ED, aiming to assess whether there is a correlation between the LUS sonographic appearance, assessed blindly across 12 lung fields, and the etiopathogenetic agent of pneumonia (bacterial and viral) detected with molecular syndromic panels (MSPs) and respiratory cultures obtained with BAL.

results64 patients were enrolled (mean age 73.3 ± 14.6) with 11 diagnosed as viral pneumonia and 53 as bacterial pneumonia. Bacterial pneumonias were more commonly associated with consolidation (2.9 ± 2.2 vs. 1.5 ± 0.9, p < 0.01) and a higher incidence of pleural effusion (0.9 ± 1.3 vs. 0.3 ± 0.6, p < 0.01). Viral pneumonias were more often associated with interstitial syndrome (4.9 ± 3.3 vs. 0.5 ± 1.3, p < 0.01) and small subpleural consolidations (0.9 ± 1.8 vs. 0.2 ± 0.6, p = 0.01). The mean LUS score was significantly higher in bacterial than in viral pneumonia with a AUC of 0.81 (95% CI 0.68-0.93).

conclusionsViral pneumonia is usually associated with interstitial syndrome and small subpleural consolidations; on the other hand, bacterial pneumonia is usually associated with consolidation, and pleural effusion.

Indexed as

Bronchoalveolar lavageBronchoscopyLung ultrasoundMolecular syndromic panelsPCR

Identifiers

PMID41307635
PMCPMC12660545

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.