ReviewDiscover oncology2025
Single-cell sequencing reveals the complexity of cutaneous T-cell lymphoma.
Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Epigenetic dysregulation in mycosis fungoides and sézary syndrome.Frontiers in cell and developmental biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cutaneous T-cell lymphoma (CTCL) is a type of lymphoma that affects the skin and has various subtypes with different features. It can be either slow-growing or aggressive and currently has limited treatment options, causing a significant impact on patients' quality of life. However, more research is needed to fully understand the underlying causes of the disease. Single-cell sequencing technology shows promise in comprehending the complex genome and microenvironment of CTCL. By analyzing the molecular status of each tumor cell, this approach can provide insights into tumor heterogeneity, microenvironment composition, and cell state transitions, tailoring treatment strategies to individual patients. In this review, we highlight recent research progress in CTCL via single-cell sequencing, focusing on gene alterations and related biomarkers, disease origin and progression, and the tumor microenvironment. We aim to provide examples of single-cell studies that can help inform new drug discovery and contribute to improved treatment strategies for patients with CTCL.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.