Evidence map›Paper›PMID 41308499›Full record

ArticleBrazilian journal of otorhinolaryngology

Lymphocyte-to-monocyte ratio as a clinical predictor in sudden sensorineural hearing loss.

Elvan Onan, Ozgur Surmelioglu, Caglar Eker, Muhammed Dagkiran, Ilda Tanrisever Pehlivan, Berk Alsancak, Suleyman Ozdemir, Ozgur Tarkan, Mustafa Mete Kiroglu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elvan OnanÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey. Electronic address: uygurelvan@hotmail.com.
Ozgur SurmeliogluÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Caglar EkerÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Muhammed DagkiranÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Ilda Tanrisever PehlivanÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Berk AlsancakÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Suleyman OzdemirÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Ozgur TarkanÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.
Mustafa Mete KirogluÇukurova University, Faculty of Medicine, Department of Otorhinolaryngology, Adana, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluates the prognostic significance of systemic inflammatory markers ‒ NLR, LMR, PLR, and SII ‒ in patients with SSNHL.

methodsThis retrospective study included 120 patients diagnosed with SSNHL at the Otolaryngology Department of Hospital. Medical records from both SSNHL and healthy control groups were reviewed to collect demographic data, pure tone audiometry results, and routine blood parameters. Hearing recovery was assessed at baseline and after two months using Siegel's criteria, and patients were categorized as either recovered (complete, partial, or slight recovery) or unrecovered.

resultsCompared to controls, SSNHL patients showed significantly elevated neutrophil counts, platelet levels, NLR, PLR, and SII values. Statistically significant differences were observed between recovered and unrecovered groups in neutrophil count (p = 0.021), lymphocyte count (p = 0.001), PDW (p = 0.042), NLR (p = 0.001), PLR (p = 0.001), LMR (p = 0.001), and SII (p = 0.001). Logistic regression analysis identified low LMR as a significant independent predictor of poor prognosis (R² = 0.271).

conclusionElevated NLR, PLR, and SII values may reflect inflammatory processes and microvascular dysfunction in SSNHL. Among these, LMR emerged as a novel and potentially valuable prognostic biomarker for predicting treatment outcomes. LEVEL OF EVIDENCE: 3:

Indexed as

Hearing Loss, SensorineuralHearing Loss, SuddenLymphocytesMonocytesAdultAgedAudiometry, Pure-ToneBiomarkersCase-Control StudiesFemaleHumansLeukocyte CountLymphocyte CountMaleMiddle AgedNeutrophilsBiomarkersInflammatory markersLymphocyte-to-monocyte ratioNeutrophil-to-lymphocyte ratioPlatelet-to-lymphocyte ratioSudden Sensorineural Hearing Loss (SSNHL)

Identifiers

PMID41308499
PMCPMC12702166

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.