Evidence map›Paper›PMID 41309556›Full record

Trial reportNature communications2025

Flexible time-restricted eating combined with exercise in a free-living setting for middle-aged women with overweight/obesity: a randomized controlled trial.

Zihan Dai, Masashi Miyashita, Eric Tsz-Chun Poon, Xiao Yu Tian, Angus Pak-Hung Yu, Cindy Hui-Ping Sit, Stephen Heung-Sang Wong

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zihan DaiDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.ORCID http://orcid.org/0009-0001-0071-0278
Masashi MiyashitaDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.
Eric Tsz-Chun PoonDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.
Xiao Yu TianSchool of Biomedical Sciences, Heart and Vascular Institute, Faculty of Medicine, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.ORCID http://orcid.org/0000-0003-3472-9898
Angus Pak-Hung YuDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.
Cindy Hui-Ping SitDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China.
Stephen Heung-Sang WongDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, China. hsswong@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-6821-4545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity poses a significant public health challenge among middle-aged women, driven by physiological changes associated with aging and menopause. This parallel-group, assessor-blinded, four-arm randomized controlled trial investigated the effects of 12-week 8-hour flexible time-restricted eating (flexTRE) and aerobic exercise (EX), alone or in combination (flexTRE+EX), on body composition and metabolic health in a free-living setting. Participant enrolment began on September 1

Indexed as

ExerciseObesityOverweightAdultBody CompositionFemaleHong KongHumansMiddle AgedTreatment Outcome

Identifiers

PMID41309556
PMCPMC12660762

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.