Evidence map›Paper›PMID 41310154›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

DNA Origami and Its Applications in Synthetic Biology.

Yaning Fang, Xuexin Chen, Qingsheng Qi, Min Lin, Quanfeng Liang

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. DNA Origami and Its Applications in Synthetic Biology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaning FangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, P. R. China.
Xuexin ChenState Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, P. R. China.
Qingsheng QiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, P. R. China.
Min LinCollege of Agriculture, Henan University, Kaifeng, 475001, P. R. China.
Quanfeng LiangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, P. R. China.ORCID https://orcid.org/0000-0002-4289-2508

Funding

National Natural Science Foundation of China 32470065
6 · The paper itself

Abstract

In recent years, DNA origami technology has advanced rapidly as a groundbreaking method for nanomanufacturing. This technology takes advantage of the unique base-pairing characteristics of DNA, and has significant advantages in constructing spatially ordered and programmable nanostructures. This capability aligns with synthetic biology's core principle of mimicking, extending, and reconstructing natural biological processes by modularly assembling artificial systems. This article provides a comprehensive overview of DNA origami's innovative applications across various domains, including cell membrane surfaces, intercellular communication, intelligent biosensing, and precise gene editing, progressing from the extracellular to the intracellular environment. Finally, this review highlights the synergistic interaction between this technology and cell-free synthetic biology, achieved through the integration of in vitro assembly and cellular regulation, thereby opening new pathways for the rational design of artificial life systems.

Indexed as

DNANanostructuresNanotechnologySynthetic BiologyBiosensing TechniquesDNAcell‐freeDNA origamigene editingsynthetic biology

Identifiers

PMID41310154
PMCPMC12786304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.