Evidence mapPaperPMID 41310342Full record

ArticleScientific reports2025

Eltrombopag olamine induces apoptosis in human breast adenocarcinoma and hepatocellular carcinoma cells through modulation of multiple apoptotic pathways.

Syed Rashel Kabir, Md Asaduzzaman, A D A Shahinuzzaman, Mohammad Taufiq Alam

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Syed Rashel KabirDepartment of Biochemistry and Molecular Biology, Faculty of Science, University of Rajshahi, Rajshahi, 6205, Bangladesh. rashelkabir@ru.ac.bd.
Md AsaduzzamanDepartment of Applied Chemistry and Chemical Engineering, University of Rajshahi, Rajshahi, 6205, Bangladesh.
A D A ShahinuzzamanPharmaceutical Sciences Research Division, BCSIR Laboratories Dhaka, Council of Scientific and Industrial Research (BCSIR), Dhaka, Bangladesh.
Mohammad Taufiq AlamDepartment of Applied Chemistry and Chemical Engineering, University of Rajshahi, Rajshahi, 6205, Bangladesh. talam@ru.ac.bd.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer remains a global health challenge, driving the search for more effective therapeutic agents due to the limitations of existing treatments. We evaluated the anticancer potential of Eltrombopag olamine on MCF-7 (breast adenocarcinoma) and SMMC-7721 (hepatocellular carcinoma) cell lines. Eltrombopag olamine demonstrated dose-dependent antiproliferative effects, with IC

Indexed as

AdenocarcinomaAntineoplastic AgentsApoptosisBenzoatesBreast NeoplasmsCarcinoma, HepatocellularHydrazinesLiver NeoplasmsPyrazolesCell Line, TumorCell ProliferationFemaleHEK293 CellsHumansMCF-7 CellsSignal TransductionAntineoplastic AgentsBenzoateseltrombopagHydrazinesPyrazolesEGFRMCF-7 cellSMMC-7721 cellTNFαWNT1

Identifiers

PMID41310342
PMCPMC12673074

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.