Evidence map›Paper›PMID 41310343›Full record

ArticleScientific reports2025

Investigating the potential of dietary iron supplementation to enhance long-chain polyunsaturated fatty acid biosynthesis in Hediste diversicolor.

Andrea Villena-Rodríguez, Juan C Navarro, Inmaculada Varó, Felipe Aguado-Giménez, Júlia Pérez-Ara, Myriam Lizanda, Ignacio E Martín, Inmaculada Rasines, Óscar Monroig

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea Villena-RodríguezInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain.
Juan C NavarroInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain.
Inmaculada VaróInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain.
Felipe Aguado-GiménezPlanta de Cultivos Marinos "El Bocal", Centro Oceanográfico de Santander. Instituto Español de Oceanografía (COST‑IEO), CSIC, Monte‑Corbanera, Santander, 39012, Spain.
Júlia Pérez-AraInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain.
Myriam LizandaInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain.
Ignacio E MartínPlanta de Cultivos Marinos "El Bocal", Centro Oceanográfico de Santander. Instituto Español de Oceanografía (COST‑IEO), CSIC, Monte‑Corbanera, Santander, 39012, Spain.
Inmaculada RasinesPlanta de Cultivos Marinos "El Bocal", Centro Oceanográfico de Santander. Instituto Español de Oceanografía (COST‑IEO), CSIC, Monte‑Corbanera, Santander, 39012, Spain.
Óscar MonroigInstituto de Acuicultura Torre de la Sal (IATS), CSIC, Ribera de Cabanes, Castellón, 12595, Spain. oscar.monroig@csic.es.

Funding

Agencia Estatal de Investigación TED2021-129647B-I00Generalitat Valenciana THINKINAZUL/2021/26
6 · The paper itself

Abstract

Fatty acyl desaturases are nutritionally regulated and depend on iron (Fe) for optimal activity. We hypothesised that dietary Fe supplementation, under conditions promoting desaturase upregulation, can enhance desaturase activity and improve n-3 LC-PUFA biosynthesis in invertebrates. The present study aimed to evaluate the effects of dietary Fe supplementation on LC-PUFA biosynthesis in H. diversicolor, a commercially important polychaete, using both In vitro and in vivo approaches. The in vitro assays revealed that Fe supplementation, from both inorganic (FeSO

Indexed as

Dietary SupplementsFatty Acids, UnsaturatedIronIron, DietaryPolychaetaAnimalsFatty Acid DesaturasesFatty Acid DesaturasesFatty Acids, UnsaturatedIronIron, DietaryDesaturasesFe supplementationHediste diversicolorLC-PUFA biosynthesis

Identifiers

PMID41310343
PMCPMC12660862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.