Observational studyBMC nephrology2025
Detailed ultrasonographic assessment of calcified arteries before arterio-venous fistula construction and fistula outcomes - a prospective observational study.
Observational study in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Rapidly Progressive Medial Calcific Sclerosis in a Dialysis Patient.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundArterial calcifications (mainly mediocalcinosis) are highly prevalent in patients on hemodialysis. Severe calcifications reduce the possibility of a forearm arterio-venous fistula (AVF) construction, reduce maturation rates and increase the risk of hemodialysis access-induced distal ischemia (HAIDI). We report a prospective observational study on detailed ultrasound assessment of calcified arteries and outcomes of AVFs constructed in those conditions.
methodsIn patients referred for vascular mapping, distal, mid and proximal radial artery (RA) as well as brachial artery were assessed for grade of calcifications (B-mode), homogeneity of color Doppler (CD) and compressibility of the artery. Pulsed-wave Doppler parameters at rest and during reactive hyperemia were also assessed. Based on the results, a site for AVF construction was planned. Outcomes of constructed AVFs were assessed.
resultsIn 35 patients (mean age 68±13 years, 89% diabetics) we assessed 240 arterial sites, made 44 plans and constructed 31 AVFs/grafts. We observed several ultrasonographic phenotypes of calcified arteries. Severely calcified arteries (B-mode assessment) were heterogeneous when assessed for CD homogeneity and compressibility. Constructed AVFs/grafts had very good maturation rates (> 75%) even in a subgroup of radio-cephalic AVFs made on significantly calcified RAs (79%). There were no cases of clinically significant HAIDI.
conclusionsAVF construction with high likelihood of maturation and low likelihood of HAIDI in patients with significantly calcified arteries is possible, after proper evaluation of the artery. Homogeneity of CD and compressibility of the artery with ultrasound probe are useful additional criteria for assessing the suitability of a severely calcified artery for AVF construction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.