Evidence map›Paper›PMID 41310687›Full record

ReviewMalaria journal2025

Plasmodium knowlesi and global changes: socio-ecological drivers and challenges.

Fauzi Muh, Nabila Gusvie Qanita, Mutiara Rizqi Yuwanita, Ajeng Dwi Wusono, Aprillia Andika Rahayu, Fariha Akmalina Amirudin, Moh Egy Rahman Firdaus, Ni Kadek Dita Cahyani, Jin-Hee Han

Abstract readReview
In one paragraph

Review in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fauzi MuhDepartment of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia. fauzimuh010@gmail.com.
Nabila Gusvie QanitaDepartment of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia.
Mutiara Rizqi YuwanitaDepartment of Health Entomology, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia.
Ajeng Dwi WusonoDepartment of Health Entomology, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia.
Aprillia Andika RahayuDepartment of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia.
Fariha Akmalina AmirudinDepartment of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia.
Moh Egy Rahman FirdausInternational Institute of Molecular Mechanisms and Machines (IMol), Polish Academy of Sciences, M. Flisa 6, 02-247, Warsaw, Poland.
Ni Kadek Dita CahyaniBiology Department, Faculty of Science and Mathematics, Universitas Diponegoro, Semarang, 50275, Indonesia.
Jin-Hee HanDepartment of Epidemiology and Tropical Diseases, Faculty of Public Health, Universitas Diponegoro, Semarang, 50275, Indonesia. han.han@kangwon.ac.kr.

Funding

the Institute for Research and Community Services, Universitas Diponegoro 222-030/UN7.D2/PP/IV/2025the National Research Foundation of Korea (NRF), funded by the Ministry of Education and the Ministry of Science and ICT (RS-2023-00240627) and (RS-2025-16069701)
6 · The paper itself

Abstract

Plasmodium knowlesi, a malaria species predominantly found in Southeast Asia, is influenced by climate change in its transmission dynamics. Variations in temperature and precipitation impact both mosquito vectors and the parasites they carry. Additionally, deforestation and alterations in land use, often driven by climate change, facilitate the zoonotic transmission of the disease from simian hosts to humans. Climatic fluctuations also influence human and community behaviours, potentially altering exposure risks. Although increased awareness of climate risks may prompt behavioural changes, the attitude behaviour gap-where awareness does not necessarily translate into action-remains a significant challenge. Environmental alterations can transform mosquito habitats and breeding patterns, thereby influencing disease transmission. Community responses may create new transmission zones or modify existing ones. Furthermore, climate change may alter the distribution of natural hosts for Plasmodium knowlesi, affecting its transmission dynamics. Understanding these interconnections is crucial for addressing the impact of climate change on malaria transmission in general and specifically P. knowlesi. This review examines the spread of P. knowlesi in the context of climate change, land use changes, human behaviour and activities, human-macaque-mosquito interaction, other contributing factors, and challenges to provide insight for future research on controlling P. knowlesi in regions where interactions among humans, monkeys, and mosquitoes are intensifying due to environmental and developmental changes.

Indexed as

Climate ChangeMalariaPlasmodium knowlesiAnimalsEcosystemHumansMacacaMosquito VectorsClimate changeMalariaP. knowlesiZoonosis

Identifiers

PMID41310687
PMCPMC12765293

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.