ArticleThe Laryngoscope2026
Inflammatory Markers Stratify Surgical Outcomes in Pediatric Airway Reconstruction.
Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Inflammatory Markers Stratify Surgical Outcomes in Pediatric Airway Reconstruction.The Laryngoscope · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesRed blood cell distribution width (RDW) predicts surgical success in adult patients undergoing open airway reconstruction for laryngotracheal stenosis, but similar biomarkers in pediatrics remain unidentified. This study identifies predictors of outcomes in pediatric patients undergoing triple endoscopy or surgical airway reconstruction.
methodsA retrospective cohort study of 191 pediatric patients who underwent triple endoscopy or surgical airway reconstruction at an aerodigestive center between 4/18/2013 and 4/17/2023 was completed. Ninety-eight patients with lab values within 2 months of the procedure were included. Main outcome measures were prosthesis-free breathing at last follow-up, hospitalization length, and follow-up duration.
resultsLower RDW values were associated with prosthesis-free breathing at last follow-up (p = 0.042) and shorter hospitalizations (p < 0.001). Higher monocyte-to-lymphocyte ratio (MLR) and systemic inflammation response indexes (SIRI) correlated with increased length of hospitalization (p = 0.003 and p = 0.01). Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and tracheomalacia were associated with longer follow-up periods (p = 0.04). Patients with tracheomalacia and OSA prior to intervention were more likely to require tracheostomy at last follow-up (p = 0.005 and p = 0.041).
conclusionsRDW may predict long-term surgical success and outcomes in pediatric patients with complex airway, pulmonary, and upper digestive tract disorders. Serologic markers including SIRI, MLR, NLR, and PLR may also predict outcomes. Patient demographics and surgical type did not correlate with long-term outcomes, but patients with tracheomalacia and OSA were more likely to require tracheostomy at later time points. LEVEL OF EVIDENCE: 3:
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