Evidence map›Paper›PMID 41311305›Full record

GuidelineMycoses2025

Management of Invasive Pulmonary Aspergillosis in Intensive Care Units: Guidelines From the Fungal Infection Network of Switzerland (FUNGINOS).

F Lamoth, W C Albrich, S Ragozzino, D Bosetti, J Delaloye, C El Khoury, A Munting, V Portillo, I Reinhold, J Sumer and 22 more

Abstract readPractice Guideline
In one paragraph

Guideline in Mycoses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Diagnostic criteria for invasive pulmonary aspergillosis in COPD patients.American journal of respiratory and critical care medicine · 2026
    Article
  5. Article
  6. Successful Treatment of Carbapenem-ResistantInfection and drug resistance · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

F LamothDepartment of Medicine, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-1023-5597
W C AlbrichDivision of Infectious Diseases, Infection Prevention and Travel Medicine, HOCH Health Ostschweiz, St Gallen Cantonal Hospital, St Gallen, Switzerland.
S RagozzinoDivision of Infectious Diseases, University Hospital and University of Basel, Basel, Switzerland.
D BosettiInfection Control Program and WHO Collaborating Center, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland.
J DelaloyeDepartment of Medicine, Ensemble Hospitalier de la Côte, Morges, Switzerland.
C El KhouryDepartment of Medicine, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
A MuntingDepartment of Medicine, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
V PortilloDepartment of Medicine, Ensemble Hospitalier de la Côte, Morges, Switzerland.
I ReinholdInstitute of Translational Research, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
J SumerDivision of Infectious Diseases, Infection Prevention and Travel Medicine, HOCH Health Ostschweiz, St Gallen Cantonal Hospital, St Gallen, Switzerland.
A ZbindenUnilabs Dübendorf, Dübendorf, Switzerland.
V BättigDivision of Infectious Diseases, University Hospital and University of Basel, Basel, Switzerland.
C Beigelman-AubryDepartment of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
K BoggianDivision of Infectious Diseases, Infection Prevention and Travel Medicine, HOCH Health Ostschweiz, St Gallen Cantonal Hospital, St Gallen, Switzerland.
A ConenClinic for Infectious Diseases and Infection Prevention, Aarau Cantonal Hospital, Aarau, Switzerland.
T S FischerDepartment of Radiology and Nuclear Medicine, HOCH Health Ostschweiz, St Gallen Cantonal Hospital, St Gallen, Switzerland.
C GarzoniClinica Moncucco, Gruppo Ospedaliero Moncucco, Lugano, Switzerland.
D GoldenbergerDepartment of Clinical Bacteriology/Mycology, University Hospital Basel and University of Basel, Basel, Switzerland.
E HofmannDepartment of Infectious Diseases, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
P KhafagyDepartment of Radiology, Fribourg Cantonal Hospital, Fribourg, Switzerland.
L KernDivision of Pulmonology, Winterthur Cantonal Hospital, Winterthur, Switzerland.
G R KlegerDivision of Intensive Care Medicine, HOCH Health Ostschweiz, St Gallen Cantonal Hospital, St Gallen, Switzerland.
C Le TerrierDivision of Intensive Care, Department of Acute Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
O MarchettiDepartment of Medicine, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
J L PaganiIntensive Care Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
N J RuppDepartment of Pathology and Molecular Pathology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
P W SchreiberDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
M SiegemundDivision of Intensive Care, University Hospital and University of Basel, Basel, Switzerland.
F KadgienInfectious Diseases Clinic, University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
D NeofytosDivision of Infectious Diseases, Transplant Infectious Diseases Unit, University Hospitals of Geneva, Geneva, Switzerland.
N KhannaDivision of Infectious Diseases, University Hospital and University of Basel, Basel, Switzerland.
Fungal Infection Network of Switzerland (FUNGINOS)

Funding

Gilead FoundationMundipharma Medical Company, BaselPfizer
6 · The paper itself

Abstract

Invasive pulmonary aspergillosis (IPA) is increasingly recognised in intensive care units (ICU) affecting not only patients with classical immunosuppressive conditions but also other severely ill patients, including those with respiratory viral infections (influenza, COVID-19), advanced chronic obstructive pulmonary disease or acute and chronic liver diseases. Several expert panels have proposed definitions of IPA in different ICU settings. However, practical recommendations for its diagnostic and therapeutic approaches are scarce. Moreover, these approaches can be influenced by different parameters that may vary across countries including the case mix of ICU patients, the incidence of IPA, the prevalence of azole resistance and the availability of diagnostic tests and antifungal drugs. For these reasons, the Fungal Infection Network of Switzerland (FUNGINOS) has appointed a panel of different specialists to develop a practical guideline for the management of IPA in ICU. This article provides the executive summary of the panel conclusions and recommendations regarding the epidemiology, diagnosis, definitions and therapy of IPA in ICU.

Indexed as

Antifungal AgentsIntensive Care UnitsInvasive Pulmonary AspergillosisHumansSwitzerlandAntifungal Agentsantifungal therapyaspergilluscirrhosiscoronaviruscritical carecritically illflutracheobronchitis

Identifiers

PMID41311305
PMCPMC12661390

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.