Evidence map›Paper›PMID 41311548›Full record

ArticleACS sustainable chemistry & engineering2025

Engineered Accumulation of Protocatechuate in Corn Biomass to Enhance Biomanufacturing.

Yang Tian, Bumkyu Kim, Irem Pamukçu, Emine Akyuz Turumtay, Alexis H Tan, Victoria Saini, Ariana Irma Chavez, Anna Tang, Anna Z Su, Edward E K Baidoo and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS sustainable chemistry & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. UsingACS ES&T engineering · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yang TianJoint BioEnergy Institute, Emeryville, California 94608, United States.
Bumkyu KimDepartment of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID https://orcid.org/0000-0001-7772-9332
Irem PamukçuEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Emine Akyuz TurumtayJoint BioEnergy Institute, Emeryville, California 94608, United States.
Alexis H TanEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Victoria SainiEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Ariana Irma ChavezEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Anna TangEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Anna Z SuEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Edward E K BaidooJoint BioEnergy Institute, Emeryville, California 94608, United States.
Jorge RencoretInstituto de Recursos Naturales y Agrobiología de Sevilla, IRNAS-CSIC, Avenida de la Reina Mercedes, 10, Sevilla 41012, Spain.ORCID https://orcid.org/0000-0003-2728-7331
José C Del RíoInstituto de Recursos Naturales y Agrobiología de Sevilla, IRNAS-CSIC, Avenida de la Reina Mercedes, 10, Sevilla 41012, Spain.ORCID https://orcid.org/0000-0002-3040-6787
Timothy J DonohueWisconsin Energy Institute, University of Wisconsin-Madison, Madison, Wisconsin 53726, United States.ORCID https://orcid.org/0000-0001-8738-2467
Daniel R NogueraDepartment of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.ORCID https://orcid.org/0000-0003-0372-3063
Aymerick EudesJoint BioEnergy Institute, Emeryville, California 94608, United States.ORCID https://orcid.org/0000-0002-1387-6111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in-planta accumulation of coproducts in crops can enhance the value of lignocellulosic biomass and facilitate a sustainable bioeconomy. Corn stover represents a major renewable source of lignocellulose for the production of advanced biofuels and bioproducts. In this study, we engineered corn with a bacterial gene encoding a dehydroshikimate dehydratase (QsuB) to overproduce protocatechuate (DHBA). Transgenic corn lines accumulate up to 2.9% DHBA on a dry weight basis in leaf and stem biomass. DHBA occurs in the form of glucosides that are extractable from biomass using aqueous methanol as the solvent. The analysis of lignin did not show any evidence for the incorporation of DHBA; however, an increase in the lignin syringyl to guaiacyl ratio and a higher relative abundance of

Indexed as

2-pyrone-4,6-dicarboxylate3,4-dihydroxybenzoatebiological funnelingcoproductcorn stoverNovosphingobium aromaticivorans

Identifiers

PMID41311548
PMCPMC12648766

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.