Evidence map›Paper›PMID 41311701›Full record

ArticleFrontiers in neuroscience2025

Multimodal neuroimaging of

Xiao Gao, Xiaowei Wang, Cassandre Labelle-Dumais, Douglas B Gould, Myriam M Chaumeil

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao GaoDepartment of Physical Therapy and Rehabilitation Science, UCSF, San Francisco, CA, United States.
Xiaowei WangDepartment of Ophthalmology, UCSF, San Francisco, CA, United States.
Cassandre Labelle-DumaisDepartment of Ophthalmology, UCSF, San Francisco, CA, United States.
Douglas B GouldDepartment of Ophthalmology, UCSF, San Francisco, CA, United States.
Myriam M ChaumeilDepartment of Physical Therapy and Rehabilitation Science, UCSF, San Francisco, CA, United States.

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ULLIAN, ERIK M · 1985 to 2024
$16.8M
Mechanisms of Functional Vascular Impairment In Genetic Models of Cerebral Small Vessel DiseaseRF1NS110044 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EARLEY, SCOTT, GOULD, DOUGLAS · 2018 to 2022
$3.3M
Diversity Supplement-MassoudiR33NS115132 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAUMEIL, MYRIAM MARIANNE, EARLEY, SCOTT · 2021 to 2023
$2.6M
Vision Bioinformatics and ComputationP30EY037668 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erik M Ullian · 2025 to 2026
$2.0M
Development and validation of novel models for cerebral small vessel disease and vascular cognitive impairmentR61NS115132 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAUMEIL, MYRIAM MARIANNE, EARLEY, SCOTT · 2019 to 2020
$1.1M
NEI NIH HHS P30 EY002162NEI NIH HHS P30 EY037668NINDS NIH HHS R33 NS115132NINDS NIH HHS R61 NS115132NINDS NIH HHS RF1 NS110044
6 · The paper itself

Abstract

Introduction: Cerebral small vessel disease (cSVD) is a leading cause of stroke and vascular contributions to cognitive impairment and dementia (VCID). Studying monogenic forms of cSVD can elucidate molecular pathways that are dysfunctional in the common sporadic forms and may serve as potential therapeutic targets. Mutations in Methods: To investigate how allelic heterogeneity influences cerebrovascular phenotypes, we examined five Results: Multimodal MRI successfully identified typical cSVD-associated lesions across all Discussion: These findings demonstrate that high-field multimodal MRI can sensitively detect and differentiate cerebrovascular abnormalities among

Indexed as

Col4a1collagencSVDGould syndromeMRIvascular dementia

Identifiers

PMID41311701
PMCPMC12647094

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.