Evidence map›Paper›PMID 41311796›Full record

ArticleFrontiers in nutrition2025

Retrospective analysis of dietary fat quality and cardiovascular disease risk markers in middle-aged adults.

Yongbo Zhang, Fengling Wang, Bingsen Huang, Miaomiao Li, Changchun Du

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yongbo ZhangDepartment of Cardiovascular Medicine, Henan Provincial Chest Hospital, Zhengzhou University, Zhengzhou, China.
Fengling WangDepartment of Cardiovascular Medicine, Henan Provincial Chest Hospital, Zhengzhou University, Zhengzhou, China.
Bingsen HuangDepartment of Cardiovascular Medicine, Henan Provincial Chest Hospital, Zhengzhou University, Zhengzhou, China.
Miaomiao LiDepartment of Cardiovascular Medicine, Henan Provincial Chest Hospital, Zhengzhou University, Zhengzhou, China.
Changchun DuDepartment of Cardiovascular Medicine, Henan Provincial Chest Hospital, Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The quality of fat in food affects the cardiovascular system by means of inflammatory and lipid pathways. Objective: To assess the relationship among middle-aged persons' cardiovascular disease (CVD) risk indicators and the composition of their dietary fat. Methodology: Two hundred adults (aged 40-65) from the Henan Provincial Chest Hospital's databases were incorporated in this retrospective, hospital-based observational investigation. Dietary consumption information was taken from food frequency questionnaires that had been filled out and were kept in medical records. Employing the unsaturated-to-saturated fatty acid proportion (UFA:SFA), dietary fat composition was measured and subjects were separated into tertiles. Anthropometric variables, lipid levels (total cholesterol, LDL-C, HDL-C), and inflammation levels (hs-CRP) were obtained from pre-existing laboratory and hospital records. Results: In comparison to the lowest tertile, the highest UFA:SFA tertile had greater HDL-C (+8.29 mg/dL, Conclusion: Better lipid and inflammatory levels were associated with higher dietary fat quality, highlighting the significance of substituting unsaturated fats for saturated fats as a CVD prevention measure. However, prospective or interventional research are required to investigate causal effects, as these results are observational and demonstrate association rather than causality.

Indexed as

cardiovascular biomarkersfat quality indexhealthhyperlipidemiainflammation

Identifiers

PMID41311796
PMCPMC12649816

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.