Self-assembled silk fibroin as an interfacial reinforcer: A synergistic strategy with amorphous calcium phosphate for durable dentin bonding.

Dengwei Hong, Jinghui Lin, Bingjie Zhong, Zhicen Lu, Hao Yu

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In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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5 · Who and what money

Authors and funding

5 authors.

Dengwei HongFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Laboratory of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Jinghui LinFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Laboratory of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Bingjie ZhongFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Laboratory of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Zhicen LuFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Laboratory of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Hao YuFujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Laboratory of Fujian College and University, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited longevity of dentin bonding interfaces remains a significant challenge in dentistry, primarily due to the degradation of the hybrid layer. Incomplete penetration of dental adhesives leaves demineralized dentin collagen vulnerable to enzymatic degradation and mechanical stress. While existing approaches offer temporary solutions, dentin bonding still faces incomplete and unsustained protection for the critical interfaces. In this study, we explored an innovative dual-action biomimetic strategy combining silk fibroin (SF) and amorphous calcium phosphate (ACP) to address long-term stabilization of the dentin-adhesive interface. SF rapidly formed self-assembled fibrous network in demineralized dentin collagen. While 0.1 % and 1 % SF maintained high microshear bond strength (μSBS) values after 10,000 thermocycles, performance declined after 30,000 thermocycles (

Identifiers

PMID41312136

DOI10.1016/j.mtbio.2025.102526

PMCPMC12648620

What Socratic holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.