ArticleCanadian liver journal2025
An association between antibiotic usage during pregnancy and the subsequent development of autoimmune hepatitis.
Article in Canadian liver journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Autoimmune Hepatitis: A Review of Molecular Mechanisms and Research Gaps in African Populations.Biology · 2026Review
- A hepatology hero rides off into the sunset: A tribute to Dr Gerald Minuk.Canadian liver journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Whether the incidence of autoimmune hepatitis (AIH) is higher in women prescribed antibiotics during pregnancy remains to be determined. Methods: Administrative databases and hospital abstracts were reviewed to identify all pregnant women in the province of Manitoba from 1996 to 2001 who were prescribed antibiotics during pregnancy and subsequently diagnosed with AIH until 2020. Results: In this study, 70,666 pregnant women were identified during the 5-year period. Antibiotics were prescribed in 11,654 (16.5%). AIH was subsequently diagnosed in more mothers who were prescribed antibiotics than in those who were not (82/11,654 [0.7%] versus 166/58,975 [0.28%], Conclusions: These results describe an association between mothers prescribed antibiotics during pregnancy and the subsequent development of AIH.
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Registered trials
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