Evidence mapPaperPMID 41313426Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2026

Cost-effectiveness of Freestyle Libre Systems for People with Type 2 Diabetes Mellitus on Basal Insulin Therapy in the Netherlands: An Economic Evaluation from a Societal Perspective Within a Publicly Funded Healthcare System.

Peter van Dijk, Chris Chesters, Jack Timmons, Kirk Szafranski, Julia Bakker, Fleur Levrat-Guillen

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Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Peter van DijkIsala, Department of Internal Medicine, Diabetes Center, Zwolle, The Netherlands.
Chris ChestersAbbott Diabetes Care, Maidenhead, Vanwall Business Park, Berkshire, UK, SL6 4XE. chris.chesters@abbott.com.ORCID http://orcid.org/0009-0009-2209-9754
Jack TimmonsFormerly of Abbott Diabetes Care, Alameda, CA, USA.
Kirk SzafranskiEVERSANA, Burlington, ON, Canada.
Julia BakkerIsala, Department of Internal Medicine, Diabetes Center, Zwolle, The Netherlands.
Fleur Levrat-GuillenAbbott Diabetes Care, Maidenhead, Vanwall Business Park, Berkshire, UK, SL6 4XE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHealthcare expenditure for the treatment of type 2 diabetes mellitus (T2DM) in the Netherlands is high, mainly due to the cost of treating diabetes-related complications. Guidelines recommend sensor-based glucose monitoring systems for people living with T2DM and using insulin, but these are not reimbursed in the Netherlands for those using basal insulin only. The objective of this study was to assess the cost-effectiveness of glucose monitoring with FreeStyle Libre systems (FSL), compared with capillary-based self-monitoring of blood glucose (SMBG), for people living with T2DM on basal insulin, from the perspective of the Dutch publicly funded healthcare system.

methodsThe patient-level microsimulation model DEDUCE (DEtermination of Diabetes Utilities, Costs, and Effects) was used to estimate the incidence of complications and acute diabetes events (ADEs; hypoglycemia and diabetic ketoacidosis). The effect of FSL was modeled as a 0.5% reduction in glycated hemoglobin level, which DEDUCE translates to a lower rate of complications, and as reductions in ADEs and absenteeism. Costs (in 2024 euros) and utilities were discounted at 3% and 1.5%, respectively. Outcomes were assessed as quality-adjusted life years (QALYs).

resultsFSL was associated with 0.53 more QALYs than SMBG (12.77 vs. 12.24), at an additional cost of €8021. The resulting incremental cost-effectiveness ratio (ICER) for FSL versus SMBG was €15,181/QALY. The increased acquisition cost of FSL (€19,738) was partially offset by reductions in costs associated with complications, ADEs, and absenteeism. Probabilistic sensitivity analysis showed that FSL was 52% likely to be cost-effective at a willingness-to-pay threshold of €20,000/QALY, and > 99% likely at thresholds ≥ €40,000/QALY. FSL had an ICER of below €50,000/QALY in all scenarios investigated.

conclusionFrom a Dutch publicly funded healthcare system perspective, FSL can be considered to be cost-effective compared with SMBG for people living with T2DM on basal insulin therapy.

Indexed as

Basal insulinContinuous glucose monitoringCost-effectiveness analysisFreeStyle libre systemNetherlandsType 2 diabetes mellitus

Identifiers

PMID41313426
PMCPMC12909732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.