Evidence mapPaperPMID 41313534Full record

ReviewDigestive diseases and sciences2026

Diet in Inflammatory Bowel Diseases: Efficacy, Tolerability, and Microbiome Effects Toward Personalized Management.

Francesco Calabrese, Andrea Pasta, Elena Formisano, Elisa Marabotto, Manuele Furnari, Livia Pisciotta, Patrizia Zentilin, Edoardo G Giannini, Giorgia Bodini

Abstract readReview
In one paragraph

Review in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco CalabreseGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy. calabrese.francesco.93@gmail.com.
Andrea PastaGastroenterology Unit, Department of Internal Medicine, University of Genoa, 16132, Genoa, Italy.
Elena FormisanoGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Elisa MarabottoGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Manuele FurnariGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Livia PisciottaGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Patrizia ZentilinGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Edoardo G GianniniGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.
Giorgia BodiniGastroenterology Unit, Department of Internal Medicine, University of Genoa, IRCCS-Ospedale Policlinico San Martino, Viale Benedetto XV, 6, 16132, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInflammatory bowel disease (IBD) is increasingly recognized as a condition in which diet is not only a trigger for symptoms but also a potential tool for disease modulation. Mounting evidence links dietary patterns and specific nutrients to intestinal inflammation, microbiome composition, and mucosal repair, opening new avenues for personalized therapy. DIET

interventionsExclusive and partial enteral nutrition remain among the most effective nonpharmacologic strategies in Crohn's disease, while emerging data support the Mediterranean diet, specific carbohydrate diet, and low Fermentable Oligo-, Di-, Mono-saccharides And Polyols (FODMAP) approaches for symptom relief and quality-of-life improvement. GAPS AND FUTURE DIRECTIONS: Nevertheless, evidence is often heterogeneous, with variability in dietary protocols, endpoints, and patient populations, making firm recommendations challenging. Adherence and long-term sustainability remain major barriers, underscoring the need for realistic, patient-centered approaches. By integrating current findings with clinical practice, diet can evolve from supportive care to a central component of multidisciplinary IBD management-if guided by robust evidence and tailored to individual needs. As research continues to refine the role of specific foods, nutrients, and patterns, dietary therapy holds promise not only to complement pharmacologic treatments but also to address the broader nutritional and metabolic needs of patients living with IBD.

Indexed as

Crohn DiseaseDietGastrointestinal MicrobiomeInflammatory Bowel DiseasesPrecision MedicineDiet, MediterraneanHumansTreatment OutcomeCrohn’s diseaseExclusion dietGut microbiotaLow-FODMAP dietUlcerative colitis

Identifiers

PMID41313534
PMCPMC13201316

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.