Evidence map›Paper›PMID 41315730›Full record

ArticleCommunications engineering2025

Reliable and efficient transcranial magnetic stimulation-electroencephalography (TMS-EEG) using ultra-thin active electrodes.

Johannes Gruenwald, Leonhard Schreiner, Sebastian Sieghartsleitner, Alexandru Buzamat, Giovanni Lombardi, Antonio Calzone, Marco Fummo, Slobodan Tanackovic, Marian-Silviu Poboroniuc, Rossella Spataro and 3 more

Abstract read
In one paragraph

Article in Communications engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Johannes Gruenwaldg.tec medical engineering GmbH, Schiedlberg, Austria. gruenwald@gtec.at.ORCID http://orcid.org/0000-0001-7286-5976
Leonhard Schreinerg.tec medical engineering GmbH, Schiedlberg, Austria.ORCID http://orcid.org/0009-0004-3272-6866
Sebastian Sieghartsleitnerg.tec medical engineering GmbH, Schiedlberg, Austria.ORCID http://orcid.org/0009-0007-9222-9409
Alexandru BuzamatFaculty of Electrical&Power Engineering and Applied Informatics, Gheorghe Asachi Technical University, Iaşi, Romania.
Giovanni Lombardig.tec medical engineering GmbH, Schiedlberg, Austria.
Antonio Calzoneg.tec medical engineering GmbH, Schiedlberg, Austria.
Marco Fummog.tec medical engineering GmbH, Schiedlberg, Austria.
Slobodan Tanackovicg.tec medical engineering GmbH, Schiedlberg, Austria.
Marian-Silviu PoboroniucFaculty of Electrical&Power Engineering and Applied Informatics, Gheorghe Asachi Technical University, Iaşi, Romania.
Rossella SpataroIntensive Neurorehabilitation Unit, Villa delle Ginestre Hospital, A.S.P. Palermo, Palermo, Italy.
Agnese ZazioNeurophysiology Lab, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Marta BortolettoMoMiLab, IMT School for Advanced Studies Lucca, Lucca, Italy.
Christoph Gugerg.tec medical engineering GmbH, Schiedlberg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial magnetic stimulation combined with electroencephalography enables direct assessment of cortical excitability and connectivity via stimulation-evoked responses. While passive electrodes remain the gold standard, they require extensive preparation and are sensitive to contact quality, whereas active electrodes are easier to use but limited by increased height and larger decay artifacts. Here we introduce an ultra-thin active electrode system combined with hardware- and software-based artifact suppression. We collected electroencephalographic data from 10 healthy adults in Austria in 2024, recording brain responses with both active and passive electrodes during stimulation of the left primary motor cortex. We analyzed early and late responses for similarity and amplitude variability and found high consistency between electrode types, with stable waveforms after 20-30 trials. Response amplitudes did not differ significantly between electrode types. These findings demonstrate that active electrode systems can provide reliable and efficient recordings, supporting their broader use in stimulation-electroencephalography research.

Identifiers

PMID41315730
PMCPMC12663230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.