ArticleScientific reports2025
Alterations in neuroinflammatory and neurodegenerative biomarkers among long-term residents of a critically polluted area: a cross-sectional comparative study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Ambient air pollution is increasingly recognized as an emerging risk factor for neurodegenerative diseases. However, evidence from community-based biomarker studies in highly polluted Indian regions remains sparse. To investigate the neuroinflammatory and neurodegenerative effects of chronic exposure to ambient air pollutants in long-term residents of a critically polluted area compared to a control region. This cross-sectional study included 203 adults (aged 40-60) residentially exposed to critical levels of air pollutants for ≥ 10 years and 202 geo-demographically matched controls residing at locations with very low / minimal air pollution. Air pollutant levels across all seasons were measured according standard protocols. Blood samples were analyzed for neurological biomarkers (viz. Aβ
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