ArticleEuropean journal of clinical nutrition2026
Iron status in women of reproductive age in Switzerland: the role of inflammation and ferritin thresholds for the prevalence of iron deficiency-a cross-sectional study.
Article in European journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesIron deficiency in women of childbearing age remains a public health challenge, but prevalence data in high-income countries is scarce and the role of predictors remains uncertain. We determined the prevalence of iron deficiency in women in Switzerland and assessed the influence of BMI, inflammation, and age on iron status. In addition, we determined the ferritin concentration below which hemoglobin (Hb) starts to decline. SUBJECTS/
methodsThis is a secondary, pooled data analysis including data from 26 studies conducted in Switzerland between 2009 and 2020. Participants were a convenience sample of generally healthy women aged between 18 and 54 years (n = 2709).
resultsThe prevalence of iron deficiency in women (median 23.3 years; IQR: 21.1-26.4) was 18.9%, while 4.7% of the women were anemic and 3.3% were iron deficient anemic. The prevalence of overweight (BMI ≥ 25 kg/m
conclusionsIn this convenience sample of young women in Switzerland, one in five was iron deficient and one in 30 was anemic due to iron deficiency. Controlling ferritin concentrations for inflammation did not substantially affect the prevalence of iron deficiency, indicating that such corrections are redundant in a healthy population with a low prevalence of inflammation. Impaired erythropoiesis was observed when the ferritin concentration fell below 28.5 µg/l, providing further evidence for a physiologically based ferritin threshold to identify the onset of iron-deficient erythropoiesis.
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