Evidence mapPaperPMID 41315978Full record

ArticleBMC cardiovascular disorders2025

Nonlinear relationship between the serum uric acid-to-high density lipoprotein cholesterol ratio and short-term readmission in chronic heart failure: a retrospective cohort study.

Leilei Guo, Ping Liu, Lina Cai, Li Hu, Yueshan Zhou

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Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Leilei GuoDepartment of Cardiology, Jiang You People's Hospital, Jiang You City, 621700, Si Chuan, China. guoleilei1984@163.com.ORCID 0009-0005-3404-2115
Ping LiuDepartment of Anesthesiology, Jiang You People's Hospital, Jiang You City, 621700, Si Chuan, China.
Lina CaiDepartment of Cardiology, Jiang You People's Hospital, Jiang You City, 621700, Si Chuan, China.
Li HuDepartment of Cardiology, Jiang You People's Hospital, Jiang You City, 621700, Si Chuan, China.
Yueshan ZhouDepartment of Cardiology, Jiang You People's Hospital, Jiang You City, 621700, Si Chuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to examine the relationship between the serum uric acid-to-high density lipoprotein cholesterol ratio (UHR) and short-term readmission risk in patients with heart failure.

methodsIn this retrospective cohort study, we analyzed clinical data from Zigong Fourth People's Hospital (December 2016 to June 2019) using multivariate logistic regression, restricted cubic splines, and subgroup analyses to examine the independent association between UHR and short-term readmission risk.

resultsThe analysis included 1795 participants, of whom 58.4% were female and 53.7% were aged 60-79 years. Our study showed that an increase of one unit in the UHR was associated with a 275% increase in 28-day readmission risk (OR = 3.75, 95% CI = 1.56-9.01, P = 0.003) after adjusting for potential confounders. The 28-day readmission risk was markedly elevated in the high UHR group (Q

conclusionsUHR demonstrated a nonlinear association with short-term readmission risk in heart failure, with an inflection point at 2.30. This association was more pronounced in octogenarians and male patients.

Indexed as

Cholesterol, HDLHeart FailurePatient ReadmissionUric AcidAgedBiomarkersChinaChronic DiseaseFemaleHumansMaleMiddle AgedNonlinear DynamicsPredictive Value of TestsPrognosisRetrospective StudiesBiomarkersCholesterol, HDLUric AcidHigh density lipoprotein cholesterolReadmission riskSerum uric acidUHR

Identifiers

PMID41315978
PMCPMC12661802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.