Evidence map›Paper›PMID 41316083›Full record

ArticleBMC pregnancy and childbirth2025

Vortex formation of cardiac bilateral ventricles in fetuses with tetralogy of fallot assessed by blood speckle-tracking echocardiography.

Yushan Liu, Dan Zhou, Yang Yang, Pan Yang, Shuhao Song, Shi Zeng

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yushan LiuDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China.
Dan ZhouDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China.
Yang YangDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China.
Pan YangDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China.
Shuhao SongDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China.
Shi ZengDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital of Central South University, 139 Renmin Road (M), Changsha, Hunan, 410011, China. doctorzshi@163.com.

Funding

National Natural Sciences Foundation of China 81871372Natural Science Foundation of Changsha kq2208341Natural Science Foundation of Hunan Province 2023JJ30743
6 · The paper itself

Abstract

backgroundTo analyze the vortex characteristics of the cardiac bilateral ventricles in fetuses with tetralogy of Fallot (TOF) using a high–frame rate ultrasound with blood speckle-tracking (BST).

methodsA prospective cross-sectional study of 35 fetuses with TOF and 35 gestational age-matched controls was conducted. Fetuses with TOF were classified as mild to moderate TOF or severe TOF based on pulmonary annular diameter z-scores. The number, position, length, width, area and duration of the vortex in the bilateral ventricles were recorded by BST echocardiography. Correlations between the vortex characteristics and cardiac morphology parameters, as well as ventricular function, were assessed in fetuses with TOF.

resultsThe fetuses with TOF exhibited larger and longer duration vortex in the right ventricle (RV) than that of the controls (all P < 0.05). Linear regression analysis demonstrated that vortex area of RV was positively related to sphericity index (SI) of RV, isovolumic relaxation time (IRT) and myocardial performance index of RV in the fetuses with TOF (all P < 0.001). In fetuses with severe TOF, The vortex in RV was located closer to the cardiac apex and the vortex in the left ventricle (LV) was larger than that in normal fetuses (all P < 0.05). Vortex area of LV only in fetuses with severe TOF was slightly positively correlated with LV-IRT (P = 0.038).

conclusionsThe fetuses with TOF exhibited special vortex characteristics in RV, and some vortex characteristics, especially vortex area in RV, were closely related to RV anatomical and functional abnormalities. Further study is needed to explore the diagnostic and prognostic value of vortex characteristics in fetuses with congenital heart disease.

Indexed as

EchocardiographyFetal HeartHeart VentriclesTetralogy of FallotUltrasonography, PrenatalAdultCase-Control StudiesCross-Sectional StudiesFemaleGestational AgeHumansPregnancyProspective StudiesBlood speckle-tracking echocardiographyFetusTetralogy of fallotVortex

Identifiers

PMID41316083
PMCPMC12664186

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