Evidence map›Paper›PMID 41316431›Full record

ReviewEuropean journal of medical research2025

Neural regulation of lung cancer: from mechanisms to clinical implications.

Lijia Xu, Xiaokui Sun, Yundan Yao, Hao Fang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Role of the Nervous System in Lung Disease.Current neurology and neuroscience reports · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lijia XuDepartment of Respiratory Medicine, Hangzhou Linping District Traditional Chinese Medicine Hospital, Hangzhou, 311106, Zhejiang, China.
Xiaokui SunDepartment of Respiratory Medicine, Hangzhou Linping District Traditional Chinese Medicine Hospital, Hangzhou, 311106, Zhejiang, China.
Yundan YaoDepartment of Respiratory Medicine, Hangzhou Linping District Traditional Chinese Medicine Hospital, Hangzhou, 311106, Zhejiang, China.
Hao FangDepartment of Respiratory Medicine, Hangzhou Linping District Traditional Chinese Medicine Hospital, Hangzhou, 311106, Zhejiang, China. 717976025@qq.com.

Funding

the Linping District Science and Technology Project LPWJ2023-02-25
6 · The paper itself

Abstract

Lung cancer exhibits extremely high incidence and mortality rates among all malignancies, and its behavior is closely associated with the nervous system. Researchers have found that the nervous system influences the hallmark capabilities of lung cancer, such as proliferation, stemness, invasion, metastasis, treatment resistance, metabolic reprogramming, immune surveillance evasion, and angiogenesis. Conversely, lung cancer and anti-tumor therapies also affect the nervous system. The emergence of this knowledge has in turn provided new opportunities for lung cancer treatment and the innovation of therapeutic concepts. This review comprehensively summarizes the interaction between the nervous system and lung cancer based on the logical framework of cancer hallmarks. What's more, we also conclude several novel anti-tumor strategies based on cancer neuroscience to facilitate further implication and clinical transition.

Indexed as

Lung NeoplasmsNervous SystemAnimalsHumansCancer hallmarkCancer neuroscienceDrug repurposingLung cancer

Identifiers

PMID41316431
PMCPMC12661684

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.