ArticleResearch report (Health Effects Institute)2025
REACH-OUT: Race, Ethnicity, and Air Pollution in COVID-19 Hospitalization OUTcomes.
Article in Research report (Health Effects Institute), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
12 authors.
Funding
Abstract
introductionDetermining whether chronic exposure to air pollution contributes to observed disparities in COVID-19 outcomes requires integrating multiple determinants of patient vulnerability to COVID-19, given the complex interactions that contribute to health disparities. Exposure to adverse social and structural factors heightens vulnerability to environmental exposures, potentially resulting in increased risk of unfavorable COVID-19 outcomes. Additionally, as populations are often exposed to various co-occurring adverse factors in the setting of disinvested neighborhoods and communities, examining such factors individually may not be sufficient to fully understand how they may modify the effects of air pollutant exposures. In an effort to explain COVID-19-related disparities observed in New York City (NYC
methodsWe used harmonized electronic health record (EHR) data from five healthcare systems in NYC to derive a study population of hospitalized or emergency department (ED) patients diagnosed with COVID-19 from March 1, 2020, through February 28, 2021, who had a NYC zip code of residence. To reduce potential selection bias, we also constructed a subset of the study population restricted to patients with residential zip codes in the typical catchment area of the hospitals affiliated with the EHR data repository. We estimated air pollutant concentrations for fine particulate matter (PM
resultsExposures to NO
conclusionsWhen limiting to individuals in the hospital's typical catchment areas, the observed positive associations between air pollutant exposures and COVID-19-related morbidities such as ARDS, pneumonia, and use of dialysis were strongest in areas with higher neighborhood-level environmental vulnerability. Inverse associations between air pollutant exposures and severe outcomes like death and use of mechanical ventilation were unexpected findings that highlighted challenges in examining such associations at the population level in NYC.
Indexed as
Identifiers
41316683PMC12663533What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.