ArticleChemistry & biodiversity2026
Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC-MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay. A total of 27 compounds are identified from SiEE with varied physicochemical properties. Various biological properties of the identified compound are predicted based on online PASS prediction. The ADME and toxicity profile analysis identified pentadecanoic acid, 13-methyl-, methyl ester as a strong CDK2 and mTOR inhibitor, suggesting anticancer potential. A dose-dependent toxicity and cytotoxicity are observed. The brine shrimp lethality assay (LC
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