Evidence map›Paper›PMID 41318480›Full record

SynthesisBMC women's health2025

The relationship between fat-soluble vitamins and uterine fibroids: a systematic review.

Sareh Dashti, Fatemeh Jalal Marvi, Negin Jazayerinezhad, Maryam Akef, Tahereh Fathi Najafi

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sareh DashtiDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.
Fatemeh Jalal MarviDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.
Negin JazayerinezhadDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.
Maryam AkefDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.
Tahereh Fathi NajafiDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran. fathinajafi@iaumshms.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUterine fibroids (UF) is a common gynecology tumor that in some cases may require hysterectomy. It is hypothesized that deficiency in fat-soluble vitamins might be a risk factor for UF. The aim of this systematic review was to evaluate the relationship between fat-soluble vitamins and UFs.

methodsThis systematic review was conducted on published articles in PubMed and Web of Science till Feb 2024 using a comprehensive search strategy.

resultsOf the initial 9161 identified articles, 31 (overall population of 55189 participants), including 17 case-control studies, 6 clinical trials, four cross-sectional studies, three cohort studies, and one Mendelian epidemiological study were reviewed. Majority of the studies evaluated the relationship between serum vitamin D and UF incidence and size. None of the reviewed studies evaluated the relationship between vitamin K and UF.

conclusionsVitamin D supplementation and intake of animal sources of vitamin A could reduce UF size. There is not enough evidence regarding the effect of vitamin K and E on UF size.

Indexed as

LeiomyomaUterine NeoplasmsVitaminsDietary SupplementsFemaleHumansRisk FactorsVitamin AVitamin DVitamin EVitamin KVitamin AVitamin DVitamin EVitamin KVitaminsLeiomyomaVitamin aVitamin dVitamin eVitamin k

Identifiers

PMID41318480
PMCPMC12801442

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.