ArticleBMC public health2025
Low pre-exposure prophylaxis (PrEP) uptake and high prevalence of sexually transmitted infections among men who have sex with men in Zhejiang Province, China: a large cross-sectional survey.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundPre-exposure prophylaxis (PrEP) demonstrates substantial efficacy in preventing human immunodeficiency virus (HIV) among men who have sex with men (MSM). However, its promotion faces barriers, with implementation raising concerns about declining condom use and a potential increase in the incidence of sexually transmitted infections (STIs). This study investigated the factors associated with PrEP uptake and STIs status among MSM to inform strategies for PrEP implementation in this group.
methodsFrom July to December 2023, a cross-sectional study was conducted among MSM in Zhejiang Province, China. Data on demographic characteristics, PrEP knowledge and uptake, sexual behaviors, and HIV testing were collected using online questionnaires. Chi-square tests were used to compare the differences between the PrEP uptake and non-uptake groups, and logistic regression was applied to analyze the associated factors with PrEP uptake.
resultsA total of 5816 MSM who met the inclusion criteria were recruited, of whom 321 (5.5%, 95% CI: 4.92%-6.08%) reported PrEP uptake. Multivariate logistic regression identified key factors associated with PrEP uptake. Positively associated factors included higher education (junior college: adjusted odds ratio [aOR]: 1.54, 95% CI: 1.02-2.33, P = 0.042; bachelor's degree: aOR: 1.81, 95% CI: 1.22-2.69, P = 0.004; master's and above: aOR: 2.50, 95% CI: 1.55-4.04, P < 0.001), having two or more sexual partners (aOR: 1.91, 95% CI: 1.17-3.10, P = 0.009), occasional condom use (aOR: 1.83, 95% CI: 1.42-2.35, P < 0.001), frequent (aOR: 2.11, 95% CI: 1.59-2.80, P < 0.001) or occasional (aOR: 1.39, 95% CI: 1.02-1.88, P = 0.035) rush popper use, and STI history (aOR: 2.82, 95% CI: 1.71-4.64, P < 0.001). Conversely, freelance occupation was inversely associated with uptake (aOR: 0.65, 95% CI: 0.43-0.99, P = 0.046).
conclusionsThe prevalence of PrEP uptake among MSM in Zhejiang Province remains relatively low. Factors including lower educational level, freelance employment, multiple sexual partnerships, occasional condom use, and rush popper use were correlated with uptake. Importantly, individuals with a history of STIs were more likely to use PrEP, underscoring the need to integrate STI screening into routine PrEP services. These findings provide a critical evidence base for promoting PrEP and for developing tailored HIV/STI prevention strategies targeting MSM.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.