Evidence map›Paper›PMID 41318913›Full record

ArticleJournal of integrative plant biology2026

Near-complete genome assembly of a transformation-efficient elite inbred line LH244 and its comparison with B73.

Kaiwen Tan, Xinxiang Liu, Zijian Wang, Zhengquan Zhang, Wei Huang, Shengnan Liu, Zhen Lin, Haiming Zhao, Hainan Zhao, Yang Liu and 5 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of integrative plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kaiwen TanState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0001-8745-1047
Xinxiang LiuBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing, 100097, China.ORCID https://orcid.org/0009-0001-7721-7764
Zijian WangState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-3203-5000
Zhengquan ZhangState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-3023-6984
Wei HuangState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-6943-5892
Shengnan LiuState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0009-4545-9169
Zhen LinState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0009-0007-8204-4339
Haiming ZhaoState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-1600-9619
Hainan ZhaoState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-0235-6126
Yang LiuState Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
Fangpu HanState Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China.
Jinsheng LaiState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0001-9202-9641
Weibin SongState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0003-3496-2585
Jiuran ZhaoBeijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding, Maize Research Institute, Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing, 100097, China.
Jian ChenState Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, China Agricultural University, Beijing, 100193, China.ORCID https://orcid.org/0000-0002-1764-8394

Funding

Innovation Capabilities Construction Project of Beijing Academy of Agriculture and Forestry Sciences KJCX20210410Joint Research on Maize Improvement of Henan 2022010202National Key Research and Development Program of China 2021YFD1200701National Natural Science Foundation of China 32271541National Natural Science Foundation of China 32425041the Biological Breeding-Major Projects 2023ZD04074
6 · The paper itself

Abstract

The highly transformable maize inbred line LH244 represents an attractive model for gene discovery and genome engineering. However, the lack of a high-quality genome assembly has limited its utility in functional genomics research. Here, we present a 2.29 Gb near-complete assembly of the LH244 maize genome, with an overall base accuracy of 99.998%. Except for five gaps associated with super-long thymine-adenine-guanine (TAG) repeat arrays, all the genome sequences were assembled from telomere to telomere (T2T). Comparative analysis revealed high genetic similarity between LH244 and B73, including 80.06% genome-wide synteny and 90.92% of genes nearly identical. The LH244 genome was also compared with the complete Mo17 genome and revealed extensive intraspecific genomic variations. A total of 14 megabase-scale structural variations (SVs) were identified, including a 3.15 Mb insertion, harboring 95 genes, within the 45S rDNA array of LH244 but not in the Mo17 genome. In addition, there were five knob arrays, with an average size of 21.76 Mb and the longest of 38.70 Mb, only existing in the LH244 genome. Despite the substantial variation in knob abundance, knob-6S and knob-8L were highly conserved between LH244 and Mo17, showing strong synteny and sequence identity, as well as consistent insertion patterns of genes and transposable elements (TEs). Overall, our study provides a near-complete reference genome of an important transformable maize germplasm, which will serve as a much-needed resource for functional genomics and genome editing of maize.

Indexed as

Genome, PlantInbreedingZea maysSyntenycomparative genomicsknobLH244maizenear‐complete assembly

Identifiers

PMID41318913
PMCPMC12863028

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.