Evidence map›Paper›PMID 41319287›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

PHR-Mediated Pi Starvation Response Mobile Messenger RNAs Represent Noncoding Transcripts in Recipient Tissues.

Weiguo Dong, Shuman Wang, Chao Liu, Lulu Qiao, Kai Liu, Qiongli Jin, Xiaorong Mo, Xingxing Shen, Keke Yi, Zhiye Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weiguo DongState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Shuman WangState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Chao LiuKey Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Lulu QiaoState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Kai LiuState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Qiongli JinState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Xiaorong MoState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Xingxing ShenKey Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
Keke YiState Key Laboratory of Efficient Utilization of Arid and Semi-arid Arable Land in Northern China/Key Laboratory of Plant Nutrition and Fertilizer, Ministry of Agriculture, Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, 100097, China.
Zhiye WangState Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.ORCID https://orcid.org/0000-0002-2328-3117

Funding

Fundamental Research Funds for the Central Universities 226-2024-00102Key Technologies Research and Development Program 2021YFF1000402Key Technologies Research and Development Program 2022YFD1401600National Natural Science Foundation of China 32170262Natural Science Foundation of Zhejiang Province LZ22C150002Zhejiang Provincial Outstanding Youth Science Foundation LR24C150001
6 · The paper itself

Abstract

Nutritional deficiency for phosphate (Pi) or nitrogen triggers long-distance transport of specific mobile mRNAs, but little is known about the underlying regulation, function, and structural features of these mobile nutrient starvation-specific mRNAs. Here, heterografting and high-throughput sequencing are used to explore the landscape of long-distance mRNA transport in Arabidopsis under normal and Pi-starvation conditions. Hundreds of Pi starvation response (PSR)-specific mobile mRNAs are discovered, although their abundance is constant between normal and Pi starvation conditions. The mobility of these PSR-specific mobile mRNAs is largely dependent on PHOSPHATE STARVATION RESPONSE (PHR) function, based on mutant analysis. Notably, translatome analysis and transgenic experiments reveal that these PHR-mediated PSR-specific mobile mRNAs are translated in donor tissues, but not in recipient tissues. Further, these mobile mRNAs harbored a more unfolded 5' UTR than nonmobile mRNAs, non-PSR-mobile mRNAs, and nitrogen starvation-response mobile mRNAs. The study reveals that these PSR-specific mobile mRNAs are transported to recipient tissues to carry out a function independently of their encoded protein.

Indexed as

ArabidopsisArabidopsis ProteinsPhosphatesRNA, MessengerRNA, UntranslatedGene Expression Regulation, PlantNitrogenArabidopsis ProteinsNitrogenPhosphatesRNA, MessengerRNA, UntranslatedmRNA long‐distance transportnoncoding transcriptsphosphate starvation responsePHRRNA structure

Identifiers

PMID41319287
PMCPMC12822437

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.