Evidence mapPaperPMID 41319342Full record

ArticleChemMedChem2026

Small-Molecule Sarco/Endoplasmic Reticulum Ca

Carlos Cruz-Cortés, Silvia Micháliková, Petronela Rezbáriková, L Michel Espinoza-Fonseca, Jana Viskupičová

Abstract read
In one paragraph

Article in ChemMedChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos Cruz-CortésCenter for Arrhythmia Research, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
Silvia MichálikováCentre of Experimental Medicine, Institute of Experimental Pharmacology & Toxicology, Slovak Academy of Sciences, 84104, Bratislava, Slovakia.
Petronela RezbárikováCentre of Experimental Medicine, Institute of Experimental Pharmacology & Toxicology, Slovak Academy of Sciences, 84104, Bratislava, Slovakia.
L Michel Espinoza-FonsecaCenter for Arrhythmia Research, Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID https://orcid.org/0009-0007-1006-6504
Jana ViskupičováCentre of Experimental Medicine, Institute of Experimental Pharmacology & Toxicology, Slovak Academy of Sciences, 84104, Bratislava, Slovakia.ORCID https://orcid.org/0000-0002-4856-883X

Funding

Mechanisms and discovery of small-molecule effectors targeting cardiac ion pumpsR01HL176212 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2025 to 2025
$583k
NHLBI NIH HHS R01 HL148068NHLBI NIH HHS R01 HL176212NIH grants R01HL148068NIH grants R01HL176212Open Mobility Program grant Open-Mob-2024-11Slovak Grants APVV-24-0186Slovak Grants VEGA 2/0063/22Slovak Grants VEGA 2/0127/25
6 · The paper itself

Abstract

Impaired endoplasmic reticulum (ER) Ca

Indexed as

AntioxidantsEnzyme ActivatorsEnzyme InhibitorsPyruvaldehydeSarcoplasmic Reticulum Calcium-Transporting ATPasesSmall Molecule LibrariesAnimalsCalciumDose-Response Relationship, DrugHumansMolecular StructureStructure-Activity RelationshipAntioxidantsCalciumEnzyme ActivatorsEnzyme InhibitorsPyruvaldehydeSarcoplasmic Reticulum Calcium-Transporting ATPasesSmall Molecule LibrariesABTSactivatorscalciumdiabetesDPPHendoplasmic reticulumlipid peroxidationmethylglyoxalsarco/endoplasmic reticulum Ca2+‐ATPase

Identifiers

PMID41319342
PMCPMC12716067

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.