Evidence map›Paper›PMID 41320619›Full record

Observational studyJournal of cardiothoracic and vascular anesthesia2026

Postoperative Delirium After Coronary Artery Bypass Grafting in the United States, 2016-2021: Trends, Risk Factors, and Outcomes.

Paul Potnuru, Loay Allafy, Mohammad Khudirat, Bhuvrit R Dhakal, Mert Tore, Rita Chamoun

Abstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic and vascular anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paul PotnuruCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, UTHealth Houston, Houston, TX.
Loay AllafyCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, UTHealth Houston, Houston, TX. Electronic address: loayallafy@outlook.com.
Mohammad KhudiratCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, UTHealth Houston, Houston, TX.
Bhuvrit R DhakalCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, UTHealth Houston, Houston, TX.
Mert ToreCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Internal Medicine, Inspira Medical Center, Vineland, NJ.
Rita ChamounCenter for Outcomes Research, Institute of Perioperative Medicine, UTHealth Houston, Houston, TX; Department of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, UTHealth Houston, Houston, TX.

Funding

Research Training of Anesthesiology Physician-ScientistsT32GM135118 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Holger K. Eltzschig, Cynthia Ju · 2022 to 2026
$1.1M
NIGMS NIH HHS T32 GM135118
6 · The paper itself

Abstract

designA retrospective observational study using discharge weights and survey-specific analytic methods.

settingAnalysis of the National Inpatient Sample, representing a nationally weighted cohort of U.S. hospitalizations from 2016 to 2021.

participantsAdults aged 18 years or older who underwent isolated coronary artery bypass grafting (CABG) during the study period.

interventionNo interventions were applied. MEASUREMENTS AND MAIN

resultsPostoperative delirium (POD) was identified using validated ICD-10 codes. Using regression models, annual trends in POD, factors associated with POD, and the association of POD with mortality, postoperative complications, length of stay, and hospitalization costs were estimated. Among 911,910 CABG hospitalizations, POD occurred in 4.91% of patients, with a significant increase from 2016 to 2021 (odds ratio [OR] = 1.04 per year; p < 0.001). After multivariable adjustment, the strongest associations with POD were pre-existing dementia (adjusted [a]OR = 4.28; p < 0.001), alcohol abuse (aOR = 3.38; p < 0.001), and psychotic disorders (aOR = 2.40; p < 0.001). POD was independently associated with higher mortality (aOR = 1.85; p < 0.001), major complications, four-day longer length of stay (p < 0.001), and $8,565 higher costs (p < 0.001).

conclusionsPOD after CABG is a common and costly complication. This study identifies high-risk patients and modifiable risk factors, emphasizing the need for targeted strategies to reduce the clinical and economic burdens from POD after CABG.

Indexed as

Coronary Artery BypassDeliriumPostoperative ComplicationsAdultAgedFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesRisk FactorsUnited Statescardiac surgerycoronary artery bypass graftnational inpatient samplepostoperative delirium

Identifiers

PMID41320619
PMCPMC12683655

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.