Evidence mapPaperPMID 41320842Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2026

Cross-Sectional Associations of Body Mass Index With Disability Across High- and Middle-Income Countries in 2002-2006 and 2015-2018.

Marcos D Machado-Fragua, Séverine Sabia, Aurore Fayosse, Gabriella C Silva, Benjamin Landré, Archana Singh-Manoux

Abstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Marcos D Machado-FraguaEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.ORCID 0000-0003-2646-1510
Séverine SabiaEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.
Aurore FayosseEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.
Gabriella C SilvaEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.
Benjamin LandréEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.
Archana Singh-ManouxEpidemiology of Ageing and Neurodegenerative diseases (EpiAgeing), Université Paris Cité, Inserm U1153, Paris, France.

Funding

The Mexican Health Aging Study (MHAS)R01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · 1999 to 2025
$6.2M
Agence Nationale de la Recherche France 2030 ANR-23-PAVH-0006NIA NIH HHS R01 AG018016
6 · The paper itself

Abstract

introductionWe examined the cross-sectional association of BMI with limitations in instrumental (IADL) and basic (ADL) activities of daily living in surveys from middle- and high-income countries in 2015-2018; we also compared changes in these associations from 2002-2006 to 2015-2018.

methodsData at the 2015-2018 wave were available on 152,856 participants aged ≥ 50 years in seven nationally representative surveys from middle- (Mexico, India, and China) and high-income (the United States, SHARE-European countries, Israel, the United Kingdom, and Korea) countries. BMI was measured or self-reported, and disability in IADL and ADL was defined as limitations in at least one out of five items, respectively.

resultsThe prevalence of underweight in men/women ranged from 0.5/1.5 (UK) to 23.4%/20.6% (India), and that of obesity from 0.7/1.5 (Korea) to 35.6%/37.6% (US), respectively. Meta-analyses showed underweight to be associated with a higher odds ratio (95% CI) of IADL (men, 1.78[1.26, 2.52]; women 2.07[1.38, 3.10]) and ADL (men, 1.89[1.22, 2.91]; women 1.72[1.16, 2.53]) disability. Obesity was associated with lower IADL limitations among men (0.80 [0.67-0.96]) but not among women (1.18 [0.94-1.49]), and with higher ADL (men, 1.38 [1.14, 1.65]; women, 1.59 [1.37, 1.84]). Associations of underweight with IADL and ADL, and obesity with ADL were stronger in high-income countries. The association of BMI categories with IADL/ADL was similar in the 2002-2006 data, although the prevalence of obesity was higher in 2015-2018.

conclusionBoth underweight and obesity are associated with higher IADL and ADL disability; the stronger associations in high-income countries require further research.

Indexed as

Activities of Daily LivingBody Mass IndexObesityPersons with DisabilitiesThinnessAgedCross-Sectional StudiesDeveloped CountriesFemaleHumansIndiaMaleMiddle AgedPrevalenceUnited KingdomADL limitationsdisabilityIADL limitationsobesitysex differences

Identifiers

PMID41320842
PMCPMC13008599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.