Evidence map›Paper›PMID 41321454›Full record

ArticleFrontiers in pediatrics2025

Viral-associated septic shock in pediatric pneumonia: a retrospective analysis of pathogen-specific risks and comparative clinical features with bacterial sepsis.

Ying Cheng, Kun Chen, Hui-Ling Qian, Hong-Bo Hu

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ying ChengDepartment of Pediatrics, Maternal and Child Health Hospital of Hubei Province, Wuhan, China.
Kun ChenDepartment of Clinical Laboratory, Wuhan Ninth Hospital, Wuhan, China.
Hui-Ling QianDepartment of Pediatrics, Wuhan Ninth Hospital, Wuhan, China.
Hong-Bo HuDepartment of Clinical Laboratory, Maternal and Child Health Hospital of Hubei Province, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to determine the incidence of septic shock in hospitalized children with viral pneumonia, identify high-risk viral pathogens, and compare the clinical features between viral- and bacterial-associated septic shock cases. Methods: A retrospective study on viral respiratory infections in children hospitalized with pneumonia at two hospitals between 2022 and 2024 was conducted, with logistic regression used to assess the pathogen-specific risks. Results: Among 5,956 children with viral pneumonia, the incidence of septic shock was 1.06%, varying significantly by pathogen ( Conclusions: FluA and RSV are the key viral pathogens that predispose pediatric pneumonia patients to septic shock. Rapid viral polymerase chain reaction testing enables early pathogen identification, facilitating antibiotic de-escalation when bacterial coinfection is unlikely and promoting precise, safe antimicrobial stewardship.

Indexed as

clinical featureshospitalized childrenpathogen-specific riskpediatric pneumoniaviral septic shock

Identifiers

PMID41321454
PMCPMC12660285

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.