Evidence map›Paper›PMID 41322114›Full record

SynthesisFrontiers in pain research (Lausanne, Switzerland)2025

Ultrasound-guided acupotomy for cervical spondylosis: a systematic review and meta-analysis based on GRADE quality assessment.

Zhang Lijian, Zhang Zhen, Yuan Yuan, Zhang Nachuan

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pain research (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhang LijianOrthopedics Department, Changzhi People's Hospital, Changzhi, China.
Zhang ZhenOrthopedics Department, Changzhi People's Hospital, Changzhi, China.
Yuan YuanDepartment of Physical Education, Changzhi University, Changzhi, China.
Zhang NachuanSchool of Acupuncture and Tuina, Nanjing University of Chinese Medicine, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to evaluate the effectiveness of ultrasound-guided acupotomy (UgA) in treating Cervical spondylosis (CS), particularly in pain relief, improvement in cervical range of motion (CROM), and overall clinical efficacy, through a systematic review and meta-analysis based on GRADE quality assessment. Methods: Following PRISMA guidelines, we searched databases including PubMed, Embase, Cochrane Library, Web of Science, and CNKI, Wanfang, Weipu, and Sinomed, identifying 33 randomized controlled trials (RCTs). Inclusion criteria were: patients aged 18-70 with a diagnosis of CS, intervention with UgA, and control groups receiving placebo, physical therapy, or other conventional treatments. Primary outcomes included clinical effective rate and Visual Analog Scale (VAS) for pain, while secondary outcomes encompassed Neck Disability Index (NDI), CROM, and mean flow velocity of vertebral and basilar arteries (MFV-VA/BA). Study quality was assessed using the Cochrane Risk of Bias 2.0 tool, and meta-analysis was conducted using Stata 15.0. The GRADE approach was used to evaluate evidence quality. Results: Meta-analysis revealed that UgA significantly improved the clinical effective rate compared to control treatments (RR = 1.17, 95% CI: 1.13-1.21), with low heterogeneity ( Conclusion: UgA shows superior efficacy for pain and disability in cervical spondylosis compared to non-UgA and other acupuncture related therapies. However, heterogeneity and potential publication bias exist. It requires skilled practitioners and real-time ultrasound guidance for treatment. Future multinational randomized trials with standardized protocols are needed. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/PROSPERO, PROSPERO CRD42025649835.

Indexed as

cervical spondylosisgrademeta-analysissystematic reviewultrasound-guided acupotomy

Identifiers

PMID41322114
PMCPMC12660266

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.