Evidence map›Paper›PMID 41322142›Full record

ArticleMaterials today. Bio2025

Multifunctional DSF-loaded ICG-chelated nanozyme for four-in-one enhanced synergistic tumor therapy.

Kaiqi Hu, Chunlei Ou, Junyou Li, Wai-Wing Cheng, Ying-Yi Lee, Dinggeng He, Hung-Wing Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaiqi HuDepartment of Chemistry, The Chinese University of Hong Kong, Shatin New Territories, 999077, Hong Kong Special Administrative Region of China.
Chunlei OuCollege of Life Science, State Key Laboratory of Developmental Biology of Freshwater Fish, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, 410081, PR China.
Junyou LiDepartment of Chemistry, The Chinese University of Hong Kong, Shatin New Territories, 999077, Hong Kong Special Administrative Region of China.
Wai-Wing ChengDepartment of Chemistry, The Chinese University of Hong Kong, Shatin New Territories, 999077, Hong Kong Special Administrative Region of China.
Ying-Yi LeeDepartment of Chemistry, The Chinese University of Hong Kong, Shatin New Territories, 999077, Hong Kong Special Administrative Region of China.
Dinggeng HeCollege of Life Science, State Key Laboratory of Developmental Biology of Freshwater Fish, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, 410081, PR China.
Hung-Wing LiDepartment of Chemistry, The Chinese University of Hong Kong, Shatin New Territories, 999077, Hong Kong Special Administrative Region of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional chemotherapy remains a mainstay of cancer treatment but suffers from poor tumor selectivity and severe side effects. Addressing these limitations, we developed an innovative "4-in-1" strategy utilizing Disulfiram (DSF)-loaded Fe-based near-infrared-triggered DMTICH nanozymes integrating synergistic chemotherapy, chemodynamic therapy, photothermal therapy, and photodynamic therapy. DMTICH nanozymes can specifically release DSF and Cu

Indexed as

4-in-1 synergistic strategyEnhanced 1O2 quantum yieldMultimodal cancer therapiesNanozymes

Identifiers

PMID41322142
PMCPMC12657410

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.