Evidence mapPaperPMID 41322280Full record

ReviewJournal of pain research2025

Effectiveness of Acupuncture for Neck Pain: Systematic Review and Meta‑analysis with Trial Sequential Analysis.

Chao-Rong Xie, Zhi-Yang Zhang, Qing-Feng Tao, Xiang-Dong Luo, Qi-Xuan Fu, Lei Gao, Tong Wang, Xu Ouyang, Qin-Yi Yan, Ming-Sheng Sun and 4 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07681349 (Evaluation of the Effect of Acupuncture on 3 Dimensional Scapular Kinematics and Electromyographic Activity in Patients With Chronic Neck Discomfort), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07681349 nacompletednot on this map

Evaluation of the Effect of Acupuncture on 3 Dimensional Scapular Kinematics and Electromyographic Activity in Patients With Chronic Neck Discomfort

TypeinterventionalSponsorHualien Tzu Chi General HospitalRan2020 to 2021Enrolled50ConditionsNeck Pain ChronicArmsAcupuncture, Sham Acupuncture
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chao-Rong Xie *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Zhi-Yang Zhang *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0003-9305-0348
Qing-Feng Tao *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Xiang-Dong LuoDepartment of Neurology, Sichuan Provincial People's Hospital, Chengdu, Sichuan, People's Republic of China.
Qi-Xuan FuAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0009-6238-9991
Lei GaoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.ORCID 0009-0004-4667-9028
Tong WangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Xu OuyangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Qin-Yi YanAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Ming-Sheng SunAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Xiao WangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Fan-Rong LiangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0001-8518-9268
Hui ZhengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Ling ZhaoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose and Objectives: Acupuncture is widely utilized intervention for neck pain. Previous research has indicated that acupuncture effectively reduces pain intensity of neck pain. However, its validity remains inconclusive due to repeated significance testing. We aimed to examine the efficacy and safety of acupuncture for neck pain through meta-analysis and trial sequential analysis (TSA). Methods: We searched the OVID Medline, Embase, and Cochrane Library from inception to October 30, 2024. Randomized controlled trials (RCTs) comparing acupuncture with inert treatment, manual therapy, or other active treatments for neck pain in adults were included. Results: Twenty-six trials involving 3520 participants were included. Thirteen (50%) trials were at a low risk of bias. Acupuncture treatment demonstrated significantly greater reductions in pain intensity (mean difference [MD] ‒1.26, 95% confidence interval [CI] ‒1.77 to ‒0.75, Conclusion: In conclusion, despite the very low to moderate quality of evidence and high heterogeneity that weaken the pooled estimates, our analysis suggests acupuncture might be a safe and effectiveness therapy for neck pain, a finding corroborated by TSA. These results position acupuncture as a potential treatment option, particularly for patients with an inadequate response to conventional therapies. Future high-quality trials are unequivocally needed to strengthen this evidence.

Indexed as

acupuncturemeta-analysisneck painsystematic reviewtrial sequential analysis

Identifiers

PMID41322280
PMCPMC12664314

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.