Evidence map›Paper›PMID 41322306›Full record

ReviewFrontiers in pharmacology2025

Polyphenolic metabolites in

Jinlong Zhang, Songzhe Li, Lina Huang, Xicheng Jiang

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Nutrients · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jinlong Zhang *College of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.
Songzhe Li *College of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.
Lina HuangCollege of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.
Xicheng JiangCollege of Basic Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to elucidate the therapeutic effects of polyphenolic metabolites from Materials and methods: This review was conducted based on a comprehensive literature search of the PubMed, NCBI, and Google Scholar databases from their inception until August 2025. Key search terms included "Scutellaria baicalensis", "Scutellaria baicalensis and polyphenols," "Ischemic stroke," "cerebral infarction," "cerebral ischemia-reperfusion injury," and "toxicity." The article first summarizes the polyphenolic metabolites of S. baicalensis, such as baicalein, baicalin, wogonin, wogonoside, scutellarin, chrysin, apigenin, chlorogenic acid, and ferulic acid, and provides an overview of the pathophysiological mechanisms of ischemic stroke. The primary focus lies on elucidating the pharmacological mechanisms, potential toxic effects, and strategies for improving the bioavailability of these polyphenols in the treatment of ischemic stroke. Results: The polyphenolic metabolites of Conclusion: The polyphenolic metabolites of

Indexed as

baicaleinischemic strokeneurological deficitpolyphenolScutellaria baicalensistraditional Chinese medicine

Identifiers

PMID41322306
PMCPMC12657440

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.