Evidence map›Paper›PMID 41322621›Full record

ArticleACS omega2025

A Tetrapodal Tryptophan Derivative with Multiple Exposed Free Carboxylic Acids Blocks Host Cell Entry of Omicron SARS-Cov-2 and Respiratory Syncytial Virus.

Olaia Martí-Marí, Marta Moreno-Simoni, Ana Isabel Avilés-Alía, Luciana Rusu, Alicia Forcada-Nadal, Anmol Adhav, Maria Luisa López-Redondo, Ana-Belén Blázquez, Ana Esteban, Nereida Jiménez de Oya and 8 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Olaia Martí-MaríInstituto de Química Médica (IQM, CSIC), Madrid 28006, Spain.
Marta Moreno-SimoniInstituto de Química Médica (IQM, CSIC), Madrid 28006, Spain.
Ana Isabel Avilés-AlíaInstitute for Integrative Systems Biology (I2SysBio), UV-CSIC, Valencia 46010, Spain.
Luciana RusuInstitute for Integrative Systems Biology (I2SysBio), UV-CSIC, Valencia 46010, Spain.
Alicia Forcada-NadalInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.ORCID https://orcid.org/0000-0003-0179-4044
Anmol AdhavInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.
Maria Luisa López-RedondoInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.
Ana-Belén BlázquezDepartment of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA, CSIC), Madrid E-28040, Spain.
Ana EstebanDepartment of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA, CSIC), Madrid E-28040, Spain.
Nereida Jiménez de OyaDepartment of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA, CSIC), Madrid E-28040, Spain.
Alberto MarinaInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.ORCID https://orcid.org/0000-0002-1334-5273
Vicente RubioInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.
José Luis LlácerInstituto de Biomedicina de Valencia (IBV-CSIC), Valencia 46010, Spain.ORCID https://orcid.org/0000-0001-5304-1795
Federico GagoÁrea de Farmacología, Departamento de Ciencias Biomédicas y Unidad Asociada IQM-UAH, Universidad de Alcalá, Alcalá de Henares E-28805 Madrid, Spain.ORCID https://orcid.org/0000-0002-3071-4878
Miguel A Martín-AcebesDepartment of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA, CSIC), Madrid E-28040, Spain.
María-Jesús Pérez-PérezInstituto de Química Médica (IQM, CSIC), Madrid 28006, Spain.ORCID https://orcid.org/0000-0003-1336-7760
Ron GellerInstitute for Integrative Systems Biology (I2SysBio), UV-CSIC, Valencia 46010, Spain.
Ana San-FélixInstituto de Química Médica (IQM, CSIC), Madrid 28006, Spain.ORCID https://orcid.org/0000-0003-4271-7598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omicron sublineages of SARS-CoV-2 have accelerated the spread of the virus and facilitated immune escape. In this work, we demonstrate that compound

Identifiers

PMID41322621
PMCPMC12658634

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.