Evidence map›Paper›PMID 41322695›Full record

ArticleFrontiers in molecular biosciences2025

Platelet bioenergetics correlate with skeletal muscle respiration in a murine model of type II diabetes.

Mia S Wilkinson, Emily J Ferguson, Justin Bureau, Roan A L Haggerty-Goede, Dalia M Miller, Michelle Kuriakose, Jennifer L M H Veeneman, Patricia D A Lima, Chris McGlory, Kimberly J Dunham-Snary

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mia S WilkinsonDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Emily J FergusonSchool of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Justin BureauSchool of Kinesiology and Health Studies, Queen's University, Kingston, ON, Canada.
Roan A L Haggerty-GoedeDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Dalia M MillerDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Michelle KuriakoseDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Jennifer L M H VeenemanDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Patricia D A LimaDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Chris McGloryDepartment of Medicine, Queen's University, Kingston, ON, Canada.
Kimberly J Dunham-SnaryDepartment of Medicine, Queen's University, Kingston, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial bioenergetic research in skeletal muscle is limited by the need for biopsies. We executed a proof-of-concept study to evaluate whether blood platelets could serve as a minimally invasive surrogate for skeletal muscle mitochondrial respiration in mice. Using Seahorse extracellular flux analysis, platelet respiration was measured in healthy C57BL/6J and leptin receptor-null

Indexed as

bioenergeticsmetabolismmitochondriaplateletsskeletal muscle

Identifiers

PMID41322695
PMCPMC12660101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.