ReviewBioactive materials2026
Selenium-derived bioactive enablers for advanced therapies: From molecular redox modulation to broad-spectrum disease applications.
Review in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Exosomes in brain diseases: Mechanisms, advances, and perspectives.Bioactive materials · 2027Review
- Color-associated metabolic divergence and nutritional variation in colored cauliflower curds.Food chemistry: X · 2026Article
- A dual-pronged strategy: multi-bioactive nanoplatform synergizes ROS antidote and iron stabilization to protect against liver ischemia-reperfusion injury.Journal of nanobiotechnology · 2026Article
- A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Development and Characterization of a Guar Gum Bionanocomposite Loaded with Biogenic Selenium Nanoparticles and Its Cytotoxic Evaluation.Gels (Basel, Switzerland) · 2026Article
- Nanoparticle-based approaches for bacterial detection and therapy.Applied microbiology and biotechnology · 2026Review
- Article
- Bactericidal Activity of Selenium Nanoparticles Against a Multidrug-Resistant Pathogen: Mechanistic Hypothesis from Exploratory Proteomics.Microorganisms · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selenium nanoparticles (SeNPs)-derived bioactives have garnered considerable attention in recent years due to their unique bioactivity, favorable biocompatibility, and versatile engineering potential in the field of disease therapy. This review systematically summarizes the primary strategies for SeNPs synthesis, encompassing chemical, biological, and physical approaches, and provides an in-depth discussion on their cytotoxic mechanisms mediated through oxidative stress modulation, caspase signaling activation, mitochondrial dysfunction, and adenosine triphosphate (ATP) depletion. Notably, we highlight the multidimensional protective functions of SeNPs in scavenging reactive oxygen species, modulating inflammatory cytokines, and reshaping the immune microenvironment, elucidating their pivotal roles in antioxidation, anti-inflammation, and immune regulation. Furthermore, the review outlines the cutting-edge advances of SeNPs-derived bioactives in cancer treatment, antibacterial applications, inflammatory diseases treatment, radiation protection, reversing acute kidney injury (AKI), and antiviral applications, positioning SeNPs as next-generation therapeutic platforms. This review establishes a translational roadmap for selenium-enabled therapeutics, bridging molecular redox modulation to multimodal disease interventions, with forward-looking insights into their evolution as targeted bioactives.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.