Evidence map›Paper›PMID 41324358›Full record

ArticleeLife2025

Acidocalcisome-like vacuoles constitute a feedback-controlled phosphate buffering system for the cytosol.

Samuel Bru, Lydie Michaillat Mayer, Geun-Don Kim, Danye Qiu, Henning J Jessen, Andreas Mayer

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Inorganic phosphate and the rapid mobilization of metabolic energy in neurons.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel BruDépartement d'immunobiologie, Université de Lausanne, Epalinges, Switzerland.ORCID https://orcid.org/0000-0002-7005-8609
Lydie Michaillat MayerDépartement d'immunobiologie, Université de Lausanne, Epalinges, Switzerland.ORCID https://orcid.org/0009-0008-3292-5899
Geun-Don KimDépartement d'immunobiologie, Université de Lausanne, Epalinges, Switzerland.ORCID https://orcid.org/0000-0002-3580-2471
Danye QiuInstitute of Organic Chemistry University of Freiburg and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
Henning J JessenInstitute of Organic Chemistry University of Freiburg and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.ORCID https://orcid.org/0000-0002-1025-9484
Andreas MayerDépartement d'immunobiologie, Université de Lausanne, Epalinges, Switzerland.ORCID https://orcid.org/0000-0001-6131-313X

Funding

Deutsche Forschungsgemeinschaft 390939984European Research Council 788442Human Frontier Science Program LT000588/2019Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_204713Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_179306Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 320030-228119Volkswagen Foundation Momentum Grant 98604
6 · The paper itself

Abstract

Cells experience strong variations in the consumption and availability of inorganic phosphate (P

Indexed as

CytosolPhosphatesSaccharomyces cerevisiaeVacuolesFeedback, PhysiologicalPolyphosphatesSaccharomyces cerevisiae ProteinsPhosphatesPolyphosphatesSaccharomyces cerevisiae Proteinsacidocalcisomecell biologyenergy metabolismphosphate homeostasispolyphosphateS. cerevisiaeSPXvacuole

Identifiers

PMID41324358
PMCPMC12668673

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.