Evidence map›Paper›PMID 41324656›Full record

ReviewInnere Medizin (Heidelberg, Germany)2026

[Systemic sclerosis : A disease with multiple faces].

Caroline Evers, Jörg Distler, Oliver Distler

Abstract readReviewEnglish Abstract
In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Caroline EversKlinik für Rheumatologie, Universitätsspital Zürich, Rämistr. 100, 8091, Zürich, Schweiz.
Jörg DistlerKlinik für Rheumatologie und Hiller-Forschungszentrum, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Oliver DistlerKlinik für Rheumatologie, Universitätsspital Zürich, Rämistr. 100, 8091, Zürich, Schweiz. oliver.distler@usz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease within the spectrum of rheumatologic disorders. It is characterized by a combination of vasculopathy and inflammatory fibrosis affecting the skin and various internal organs. The disease presents with heterogeneous manifestations, which can complicate diagnosis and must be carefully considered during both monitoring and treatment. In recent decades, advances in research have expanded the range of therapeutic options available for SSc. Treatment strategies need to be tailored individually, depending on the specific clinical manifestations in each patient. The aim of this article is to provide an overview of the diverse disease manifestations and current treatment approaches in SSc. For optimal patient care, close collaboration between rheumatologists, pneumologists, gastroenterologists, cardiologists, nephrologists and general practitioners is essential.

Indexed as

Scleroderma, SystemicHumansAntifibrotic therapyConnective tissue diseasesImmunosuppression therapyRaynaud diseaseSkin fibrosis

Identifiers

PMID41324656
PMCPMC12799631

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.