ReviewMolecular biology reports2025
Glutamine reprogramming affects the tumor microenvironment and immune response in hepatocellular carcinoma.
Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Glutamine, recognized as a conditionally essential amino acid, plays a crucial role in cellular metabolism and significantly impacts the tumor microenvironment. Recent studies show that glutamine metabolism directly influences the growth and survival of hepatocellular carcinoma (HCC) cells. Recent research demonstrates that glutamine metabolism directly regulates the growth and survival of HCC cells. Additionally, it plays an instrumental role in the initiation and progression of HCC by modulating immune responses, maintaining redox balance, and facilitating metabolic reprogramming. Although current studies emphasize the diverse functions of glutamine within the HCC microenvironment, the specific mechanisms driving these processes remain not yet fully understood. This article aims to explore the metabolic pathways associated with glutamine in the context of the HCC microenvironment. It also evaluates the influence of glutamine on HCC progression and proposes future research avenues to facilitate the development of innovative therapeutic strategies for HCC management. The objective is to present novel therapeutic strategies and innovative approaches to effectively treat HCC.
Indexed as
Identifiers
41324718What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.